Three-Dimensional Printing and Tissue Engineering in Auricular Reconstruction: Global Trends, Research Frontiers, and a Translational Evidence Map

Three-dimensional (3D) printing and tissue engineering offer patient-specific strategies for auricular reconstruction, but bibliometric structure alone cannot establish technical maturity or clinical value. We combined bibliometric mapping of English-language Articles and Reviews in the Web of Science Core Collection (2014–2025) with a translational evidence map. The locked corpus comprised 169 publications (143 Articles and 26 Reviews) and 4291 citations at the 12 June 2026 snapshot. Annual output, countries, institutions, authors, journals, highly cited records, author-keyword co-occurrence, and temporal terminology were analyzed. Citation-age sensitivity used citations per publication-year (CPY), year-normalized scores, and within-year percentiles. Record-level coding evaluated technical routes, materials, cell systems, construct scale, evidence stage, scientific endpoints, reporting completeness, and barriers. Among Articles, 40 (28.0%) were in vitro only, 41 (28.7%) reached small-animal testing, four (2.8%) reached large-animal testing, and nine (6.3%) reported human evidence; only one was comparative clinical research. Chondrogenesis or extracellular-matrix outcomes were reported in 84 Articles (58.7%), whereas vascularization, clinical/aesthetic outcomes, and long-term safety/adverse events were each reported in ≤6.3%. The field is expanding internationally but remains predominantly preclinical; progress requires standardized reporting, native-cartilage comparators, long-term shape and safety assessment, and larger-animal and comparative clinical validation.

Authors

Institutions

Publication Details

Journal
Bioengineering
Published
2026-09-22
DOI
https://doi.org/10.3390/bioengineering13101095
Primary Topic
Reconstructive Facial Surgery Techniques
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Three-Dimensional Printing and Tissue Engineering in Auricular Reconstruction: Global Trends, Research Frontiers, and a Translational Evidence Map

Yuhui He, Yanyong Zhao, Ruohan Lv, Jingwei Feng
Bioengineering
Reconstructive Facial Surgery Techniques
article

Three-Dimensional Printing and Tissue Engineering in Auricular Reconstruction: Global Trends, Research Frontiers, and a Translational Evidence Map

Yuhui He, Yanyong Zhao, Ruohan Lv, Jingwei Feng
article en

Abstract

Three-dimensional (3D) printing and tissue engineering offer patient-specific strategies for auricular reconstruction, but bibliometric structure alone cannot establish technical maturity or clinical value. We combined bibliometric mapping of English-language Articles and Reviews in the Web of Science Core Collection (2014–2025) with a translational evidence map. The locked corpus comprised 169 publications (143 Articles and 26 Reviews) and 4291 citations at the 12 June 2026 snapshot. Annual output, countries, institutions, authors, journals, highly cited records, author-keyword co-occurrence, and temporal terminology were analyzed. Citation-age sensitivity used citations per publication-year (CPY), year-normalized scores, and within-year percentiles. Record-level coding evaluated technical routes, materials, cell systems, construct scale, evidence stage, scientific endpoints, reporting completeness, and barriers. Among Articles, 40 (28.0%) were in vitro only, 41 (28.7%) reached small-animal testing, four (2.8%) reached large-animal testing, and nine (6.3%) reported human evidence; only one was comparative clinical research. Chondrogenesis or extracellular-matrix outcomes were reported in 84 Articles (58.7%), whereas vascularization, clinical/aesthetic outcomes, and long-term safety/adverse events were each reported in ≤6.3%. The field is expanding internationally but remains predominantly preclinical; progress requires standardized reporting, native-cartilage comparators, long-term shape and safety assessment, and larger-animal and comparative clinical validation.

BioengineeringVol. 13(10)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), China-Japan Friendship Hospital (CN), Peking Union Medical College Hospital (CN)
Partnerships for the goals
Openalex Percentile: Top 8%
Reconstructive Facial Surgery Techniques
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.