Balloon Angioplasty for Recoarctation in Infants with Isolated Aortic Coarctation and Coarctation Associated with Other Congenital Heart Diseases

Background: For infants who underwent surgical coarctation repair and required balloon angioplasty for recoarctation within the first year of life, data are limited—especially regarding safety, mid-term efficacy, and reintervention risk factors. Methods: This retrospective study included the data of 33 infants who underwent surgical correction of CoA within their first three months of life and whose first cardiac catheterization for recoarctation—defined by a systolic echocardiographic gradient of ≥20 mmHg—was performed within the first year of life. Results: The median age at repair was 21 days, and that at angioplasty was 77 days. The peak systolic gradient decreased from 40.0 to 21.0 mmHg (p < 0.001), and the mean gradient decreased from 13.9 to 6.7 mmHg (p = 0.02). The aortic stenotic diameter increased from 3.2 to 4.1 mm (p < 0.001), and the z score increased from −4.2 to −2.7 (p < 0.001). Right arm systolic blood pressure dropped from 111.8 to 88.2 mmHg (p < 0.001); 7% of cases remained hypertensive. Complications occurred in 12% of patients, and reintervention was needed in 39.4%. Association with other congenital heart disease increased reintervention risk (OR 4.51). Follow-up gradients were as follows: 27.4 ± 10.2 mmHg (1 year), 24.6 ± 8.3 mmHg (2 years), 32.8 ± 18.8 mmHg (5 years), and 35.4 ± 23.2 mmHg (7 years). Conclusions: Early balloon angioplasty for postoperative recoarctation is safe, effective, and repeatable, with a high procedural success rate and sustained hemodynamic improvements. Reinterventions were more common in patients with additional CHD, though outcomes remained favorable.

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Journal
Journal of Cardiovascular Development and Disease
Published
2026-09-20
DOI
https://doi.org/10.3390/jcdd13090473
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Balloon Angioplasty for Recoarctation in Infants with Isolated Aortic Coarctation and Coarctation Associated with Other Congenital Heart Diseases

Jochen Pfeifer, Hashim Abdul‐Khaliq, Migdat Mustafi, Axel Rentzsch et al.
Journal of Cardiovascular Development and Disease
Congenital Heart Disease Studies
article

Balloon Angioplasty for Recoarctation in Infants with Isolated Aortic Coarctation and Coarctation Associated with Other Congenital Heart Diseases

Jochen Pfeifer, Hashim Abdul‐Khaliq, Migdat Mustafi, Axel Rentzsch, Sophie Schubert
article en

Abstract

Background: For infants who underwent surgical coarctation repair and required balloon angioplasty for recoarctation within the first year of life, data are limited—especially regarding safety, mid-term efficacy, and reintervention risk factors. Methods: This retrospective study included the data of 33 infants who underwent surgical correction of CoA within their first three months of life and whose first cardiac catheterization for recoarctation—defined by a systolic echocardiographic gradient of ≥20 mmHg—was performed within the first year of life. Results: The median age at repair was 21 days, and that at angioplasty was 77 days. The peak systolic gradient decreased from 40.0 to 21.0 mmHg (p < 0.001), and the mean gradient decreased from 13.9 to 6.7 mmHg (p = 0.02). The aortic stenotic diameter increased from 3.2 to 4.1 mm (p < 0.001), and the z score increased from −4.2 to −2.7 (p < 0.001). Right arm systolic blood pressure dropped from 111.8 to 88.2 mmHg (p < 0.001); 7% of cases remained hypertensive. Complications occurred in 12% of patients, and reintervention was needed in 39.4%. Association with other congenital heart disease increased reintervention risk (OR 4.51). Follow-up gradients were as follows: 27.4 ± 10.2 mmHg (1 year), 24.6 ± 8.3 mmHg (2 years), 32.8 ± 18.8 mmHg (5 years), and 35.4 ± 23.2 mmHg (7 years). Conclusions: Early balloon angioplasty for postoperative recoarctation is safe, effective, and repeatable, with a high procedural success rate and sustained hemodynamic improvements. Reinterventions were more common in patients with additional CHD, though outcomes remained favorable.

Journal of Cardiovascular Development and DiseaseVol. 13(9)
Donauspital (AT), Klinik Donaustauf (DE), Saarland University (DE)
Good health and well-being
Openalex Percentile: Top 10%
Congenital Heart Disease Studies
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