Leveraging Metamaterial‐Inspired Wireless Resonator for Reliable Quantitative MRI at 1.5T: Linearity, Bias, and Repeatability Assessment

ABSTRACT The accuracy of quantitative magnetic resonance imaging (qMRI) largely depends on the image signal‐to‐noise ratio (SNR). In recent years, studies on metamaterials in MRI have shown that they can significantly improve image quality through weak coupling with the body coil or receive coil. However, it is still unclear whether such coupling would affect the results of quantitative MRI. In this study, a metamaterial‐inspired wireless resonator is designed, and common clinical quantitative imaging sequences, including T1 mapping, T2 mapping, apparent diffusion coefficient (ADC), and proton density fat fraction (PDFF), are implemented on a 1.5 T MRI system. The linearity, bias, and repeatability of the quantitative results are systematically evaluated. The findings provide experimental evidence and support for the application of metamaterial‐inspired wireless resonators in quantitative MRI.