Diagnostic Yield and Therapeutic Impact of Etiologic Investigations After Status Epilepticus

Status epilepticus (SE) is a critical neurologic emergency requiring prompt symptomatic and etiologic treatment. However, the diagnostic yield of etiologic investigations remains poorly characterized. We aimed to evaluate the diagnostic yield and therapeutic impact of etiologic investigations in SE, using pretest probability strata.

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Publication Details

Journal
Neurology
Published
2026-09-21
DOI
https://doi.org/10.1212/wnl.0000000000218544
Primary Topic
Epilepsy research and treatment
Type
article
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Diagnostic Yield and Therapeutic Impact of Etiologic Investigations After Status Epilepticus

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Diagnostic Yield and Therapeutic Impact of Etiologic Investigations After Status Epilepticus

Raphael Chambon, Laurent Argaud, Stéphane Legriel, David Schnell, Charles Cerf, Isabelle Desmeulles, Olivier Lesieur, Jonathan Chelly, Candice Fontaine, Nicolas Mongardon, Abdelmalek Boubekri, Hugues Ravaux, Charles Bernard, Nicolas Pichon, Thibault Vieille, Gwenaëlle Jacq, Jean-Baptiste Lascarrou, Mehran Monchi, Pierre Bailly, Cédric Bruel, Florian Sigaud, Jean‐Pierre Quenot, Fatma Kifouche, Pascal Beuret, Sébastien Repplinger, Mehdi Marzouk, Hela Kallel, Mohamed-Lyes Hassani, Ghada Sboui
article en

Abstract

Status epilepticus (SE) is a critical neurologic emergency requiring prompt symptomatic and etiologic treatment. However, the diagnostic yield of etiologic investigations remains poorly characterized. We aimed to evaluate the diagnostic yield and therapeutic impact of etiologic investigations in SE, using pretest probability strata.

NeurologyVol. 107(7)
Inserm (FR), École Nationale Vétérinaire d'Alfort (FR), Université de Bourgogne (FR), Université de Versailles Saint-Quentin-en-Yvelines (FR), Université Paris-Est Créteil (FR), Université Paris-Saclay (FR), Paris-Est Sup (FR), Centre Hospitalier Universitaire de Grenoble (FR), Centre Hospitalier Universitaire de Nantes (FR), Centre Hospitalier Universitaire de Besançon (FR), Centre Hospitalier Universitaire de Tours (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre de recherche en Epidémiologie et Santé des Populations (FR), CHU Dijon Bourgogne (FR), Hôpital André Mignot (FR), Centre Hospitalier d'Angoulême (FR), Int'Air Medical (France) (FR), Melun Hospital (FR), Hôpitaux Universitaires Henri-Mondor (FR), Centre Hospitalier Régional Universitaire de Brest (FR), Centre Hospitalier d'Arras (FR), Hôpital Paris Saint-Joseph (FR), Centre Hospitalier de Béthune (FR), Centre Hospitalier de La Rochelle (FR), Centre Hospitalier Public du Cotentin (FR), Centre Hospitalier de Cannes (FR), Centre Hospitalier Intercommunal Toulon-La Seyne-sur-Mer (FR), Hôpital Foch (FR), Centre Hospitalier de Versailles (FR), Institut Mondor de Recherche Biomédicale (FR), Imation (United States) (US), Université Grenoble Alpes (FR)
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Epilepsy research and treatment
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