Heart Failure with Reduced Ejection Fraction (HFrEF) Normalized Through Synergistic Homoeopathic and Conventional Management: Two Case Reports

Abstract Dilated cardiomyopathy (DCM) is common at 1 in 250 of the population. It is represented by heart failure (HF) with reduced ejection fraction (HFrEF), in the absence of hypertension, valvular conditions, or coronary artery disorders. The ejection fraction (EF) of HFrEF patients is on average 30% (23–34%), which improves on conventional treatment, on average by only 4% (2–13%). The first HFrEF patient, a female 60 years old, failed to respond to Digitalis purpurea (Digitalis) from February to May 2021. Digitalis was continued when the author prescribed conventional HF treatment (HFT) from May 2021. The second female patient was 48 years old during 2022. She was treated with Digitalis from August 2023 while already on HFT prescribed by a cardiologist. The first patient responded to Digitalis after administering HFT from May, 2021. Her EF increased from 25 to 40% between early June, 2021 and the end of June, 2021, and it normalized to 60% by November, 2022. The second patient's EF increased from 26 to 30% between January and March 2023 on HFT. She was prescribed Digitalis 6 cH on August 18, 2023 having an EF of 32%. Her EF was 54% on September, 2023, which normalized to 60% by September, 2024. Homoeopathic Digitalis seems to normalize cardiomyocyte sarcomere contractile function in patients with DCM HFrEF after HFT decongested the patients. Prior to decongestion, the overstretched, thin, and weak myocardium seemed unresponsive to Digitalis.