Diagnostic accuracy of biological markers for detecting obstructive sleep apnoea

OBJECTIVES: This is a protocol for a Cochrane review (diagnostic). The objectives are as follows: To determine the accuracy of any type of biological marker found in blood, saliva, urine or breath condensation to detect obstructive sleep apnoea (OSA) in adults (> 18 years). Secondary objectives To identify the accuracy of individual biomarkers alone or in combination for detecting OSA. To find the accuracy of biological markers compared to overnight polysomnography (PSG) and home sleep apnoea test (HSAT). To investigate the accuracy of biological markers compared to overnight PSG and to HSAT in people with different degrees of severity of OSA (mild, moderate, severe). To evaluate the accuracy of biomarkers from different sample types to identify OSA.

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Publication Details

Journal
Cochrane Database of Systematic Reviews
Published
2026-09-21
DOI
https://doi.org/10.1002/14651858.cd016281
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
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article

Diagnostic accuracy of biological markers for detecting obstructive sleep apnoea

Graziela De Luca Canto, Cristine Miron Stefani, Ana Carolina Pereira Nunes Pinto, David Gozal et al.
Cochrane Database of Systematic Reviews
Obstructive Sleep Apnea Research
article

Diagnostic accuracy of biological markers for detecting obstructive sleep apnoea

Graziela De Luca Canto, Cristine Miron Stefani, Ana Carolina Pereira Nunes Pinto, David Gozal, Virgínia Fernandes Moça Trevisani, Eliete Neves Silva Guerra, Patrícia Pauletto, Carlos Flores‐Mir, Nelson Carvas
article en

Abstract

OBJECTIVES: This is a protocol for a Cochrane review (diagnostic). The objectives are as follows: To determine the accuracy of any type of biological marker found in blood, saliva, urine or breath condensation to detect obstructive sleep apnoea (OSA) in adults (> 18 years). Secondary objectives To identify the accuracy of individual biomarkers alone or in combination for detecting OSA. To find the accuracy of biological markers compared to overnight polysomnography (PSG) and home sleep apnoea test (HSAT). To investigate the accuracy of biological markers compared to overnight PSG and to HSAT in people with different degrees of severity of OSA (mild, moderate, severe). To evaluate the accuracy of biomarkers from different sample types to identify OSA.

Cochrane Database of Systematic ReviewsVol. 2026(9)
Universidade de Brasília (BR), University of Alberta (CA), Universidade Federal de Santa Catarina (BR), Universidad de Las Américas (EC), Universidade Paulista (BR), Universidade Federal do Amapá (BR), Edwards Comprehensive Cancer Center (US), University Center of Brasília (BR), Iberoamerican Cochrane Centre (ES), Universidade de Santo Amaro (BR), Universidade Federal de São Paulo (BR), Marshall University (US)
Good health and well-being
Openalex Percentile: Top 11%
Obstructive Sleep Apnea Research
DOISourceOpenAlex
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