Paediatric outpatient antimicrobial therapy and antimicrobial stewardship: literature review and implications for children’s nurses

Paediatric outpatient parenteral antimicrobial therapy (pOPAT) involves the administration of intravenous antibiotics to treat common infections in children outside the hospital setting, usually in the patient's home. Most children who receive pOPAT initially present to hospital and start by receiving antibiotic treatment in the inpatient setting. As pOPAT service provision increases, healthcare organisations need to turn their attention to antimicrobial stewardship (AMS) in the outpatient setting, while children's nurses working in the community need to understand AMS interventions and develop confidence in questioning prescribing decisions. In this article, the author reviews the literature examining the relationship between pOPAT and AMS, with a focus on the implications for children's nursing practice. The author highlights the lack of research on the role of children's nurses in pOPAT and AMS, and the importance of promoting their involvement in these aspects of service provision to improve patient outcomes and reduce the effects of antimicrobial resistance.

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Publication Details

Journal
Nursing Children and Young People
Published
2026-09-21
DOI
https://doi.org/10.7748/ncyp.2026.e1593
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
0.00
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article

Paediatric outpatient antimicrobial therapy and antimicrobial stewardship: literature review and implications for children’s nurses

Mike Minihan
Nursing Children and Young People
Antibiotics Pharmacokinetics and Efficacy
article

Paediatric outpatient antimicrobial therapy and antimicrobial stewardship: literature review and implications for children’s nurses

Mike Minihan
article en

Abstract

Paediatric outpatient parenteral antimicrobial therapy (pOPAT) involves the administration of intravenous antibiotics to treat common infections in children outside the hospital setting, usually in the patient's home. Most children who receive pOPAT initially present to hospital and start by receiving antibiotic treatment in the inpatient setting. As pOPAT service provision increases, healthcare organisations need to turn their attention to antimicrobial stewardship (AMS) in the outpatient setting, while children's nurses working in the community need to understand AMS interventions and develop confidence in questioning prescribing decisions. In this article, the author reviews the literature examining the relationship between pOPAT and AMS, with a focus on the implications for children's nursing practice. The author highlights the lack of research on the role of children's nurses in pOPAT and AMS, and the importance of promoting their involvement in these aspects of service provision to improve patient outcomes and reduce the effects of antimicrobial resistance.

Nursing Children and Young People
York Teaching Hospital NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 12%
Antibiotics Pharmacokinetics and Efficacy
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Paediatric outpatient antimicrobial therapy and antimicrobial stewardship: literature review and implications for children’s nurses — Mike Minihan · Nursing Children and Young People (2026) | TGRS Research Map | TGRS