Transcriptomic profiling of murine macrophages during Francisella tularensis infection

ABSTRACT Francisella tularensis , a virulent bioterrorism threat, subverts host immune responses within macrophages, its primary replication niche. To elucidate the temporal dynamics of the host response, we announce comprehensive time-course RNA-seq data sets capturing the global transcriptional profile of murine RAW 264.7 macrophages across early and late stages of F. tularensis infection.

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Publication Details

Journal
Microbiology Resource Announcements
Published
2026-09-21
DOI
https://doi.org/10.1128/mra.00856-26
Primary Topic
Bacillus and Francisella bacterial research
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptomic profiling of murine macrophages during Francisella tularensis infection

Inbar Cohen-Gihon, Adi Bercovich-Kinori, Ofer Cohen, Ofir Israeli et al.
Microbiology Resource Announcements
Bacillus and Francisella bacterial research
article

Transcriptomic profiling of murine macrophages during Francisella tularensis infection

Inbar Cohen-Gihon, Adi Bercovich-Kinori, Ofer Cohen, Ofir Israeli, Ma’ayan Israeli
article en

Abstract

ABSTRACT Francisella tularensis , a virulent bioterrorism threat, subverts host immune responses within macrophages, its primary replication niche. To elucidate the temporal dynamics of the host response, we announce comprehensive time-course RNA-seq data sets capturing the global transcriptional profile of murine RAW 264.7 macrophages across early and late stages of F. tularensis infection.

Microbiology Resource Announcements
Israel Institute for Biological Research (IL)
Openalex Percentile: Top 18%
Bacillus and Francisella bacterial research
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