Bilateral progressive myelinated retinal nerve fibres

Fig. 1: Bilateral progressive myelinated retinal nerve fibres. Full size image Fundus images of the right ( A ) and left ( B ) eye of a 5-year-old boy with myelinated retinal nerve fibre layers (MRNFLs) identified as white striated patches with poorly defined borders radiating from the optic discs [ 1 , 2 ]. These were observed by optometry prompted following persistent headache secondary to concussion. At the age of 17 years the dense, opaque white MRNFLs now obscure the underlying retinal vasculature in the peripapillary region of the right ( C ) and left ( D ) eye. Visual field testing observed barring of the blind spots. He remained asymptomatic. No other abnormalities such as decreased visual acuity or strabismus were identified on ophthalmology examination. Though MRNFLs were typically thought to be asymptomatic and nonprogressive, they can be associated with other ocular problems such as visual field deficits depending on the extent of myelination. Recent studies have highlighted they rarely can grow over time, as illustrated in this case [ 2 , 3 ].

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Publication Details

Journal
Eye
Published
2026-09-21
DOI
https://doi.org/10.1038/s41433-026-04865-8
Primary Topic
Cerebral Venous Sinus Thrombosis
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article
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article

Bilateral progressive myelinated retinal nerve fibres

Susan P. Mollan, Daniel Lamoureux, Sean Lazaro
Eye
Cerebral Venous Sinus Thrombosis
article

Bilateral progressive myelinated retinal nerve fibres

Susan P. Mollan, Daniel Lamoureux, Sean Lazaro
article en

Abstract

Fig. 1: Bilateral progressive myelinated retinal nerve fibres. Full size image Fundus images of the right ( A ) and left ( B ) eye of a 5-year-old boy with myelinated retinal nerve fibre layers (MRNFLs) identified as white striated patches with poorly defined borders radiating from the optic discs [ 1 , 2 ]. These were observed by optometry prompted following persistent headache secondary to concussion. At the age of 17 years the dense, opaque white MRNFLs now obscure the underlying retinal vasculature in the peripapillary region of the right ( C ) and left ( D ) eye. Visual field testing observed barring of the blind spots. He remained asymptomatic. No other abnormalities such as decreased visual acuity or strabismus were identified on ophthalmology examination. Though MRNFLs were typically thought to be asymptomatic and nonprogressive, they can be associated with other ocular problems such as visual field deficits depending on the extent of myelination. Recent studies have highlighted they rarely can grow over time, as illustrated in this case [ 2 , 3 ].

Eye
Kingston Health Sciences Centre (CA), University of Birmingham (GB)
Good health and well-being
Openalex Percentile: Top 12%
Cerebral Venous Sinus Thrombosis
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Bilateral progressive myelinated retinal nerve fibres — Susan P. Mollan, Daniel Lamoureux, et al. · Eye (2026) | TGRS Research Map | TGRS