Intra-Articular Extra-Synovial Venous-Type Synovial Haemangioma of the Knee in a Young Adult: Case Report and Literature Review of This Frequently Misdiagnosed Lesion

Objective To report a rare lesion, an intra-articular extra-synovial venous-type synovial haemangioma of the knee in a young adult and to review the relevant literature on this frequently misdiagnosed entity. Case report A 21-year-old man presented with recurrent knee effusions and pain over several years. Imaging studies revealed a well-defined, intra-articular, extra-synovial soft-tissue mass located in the anteromedial compartment of the knee. Magnetic resonance imaging (MRI) demonstrated multiple tubular structures with high signal intensity on T2- and short tau inversion recovery (STIR)-weighted images and intense, homogeneous contrast enhancement, consistent with a vascular lesion. Surgical excision was performed, and histopathological analysis confirmed a venous-type synovial haemangioma, characterized by large-calibre vascular channels lined by bland endothelial cells and containing organizing thrombi. The postoperative course was uneventful, and the patient remained disease-free at 6 months of follow-up. Conclusion Synovial haemangioma, though rare, should be considered in the differential diagnosis of recurrent knee effusions in young patients. It may mimic other benign or malignant periarticular lesions. MRI plays a key role in the evaluation, and the diagnosis can be strongly suggested by imaging, but histopathological confirmation remains essential for accurate characterization and appropriate management.

Authors

Institutions

Publication Details

Journal
International Journal of Surgical Pathology
Published
2026-09-19
DOI
https://doi.org/10.1177/10668969261478601
Primary Topic
Musculoskeletal synovial abnormalities and treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Intra-Articular Extra-Synovial Venous-Type Synovial Haemangioma of the Knee in a Young Adult: Case Report and Literature Review of This Frequently Misdiagnosed Lesion

José Juan Pozo‐Kreilinger, Mar Tapia‐Viñe, Eva Manuela Pena‐Burgos, Ignacio Millán Arredondo et al.
International Journal of Surgical Pathology
Musculoskeletal synovial abnormalities and treatments
article

Intra-Articular Extra-Synovial Venous-Type Synovial Haemangioma of the Knee in a Young Adult: Case Report and Literature Review of This Frequently Misdiagnosed Lesion

José Juan Pozo‐Kreilinger, Mar Tapia‐Viñe, Eva Manuela Pena‐Burgos, Ignacio Millán Arredondo, Félix Jesús Mora Alañón, Alfonso Tejerizo García, Mathilde de Andrade da Costa Gloria
article en

Abstract

Objective To report a rare lesion, an intra-articular extra-synovial venous-type synovial haemangioma of the knee in a young adult and to review the relevant literature on this frequently misdiagnosed entity. Case report A 21-year-old man presented with recurrent knee effusions and pain over several years. Imaging studies revealed a well-defined, intra-articular, extra-synovial soft-tissue mass located in the anteromedial compartment of the knee. Magnetic resonance imaging (MRI) demonstrated multiple tubular structures with high signal intensity on T2- and short tau inversion recovery (STIR)-weighted images and intense, homogeneous contrast enhancement, consistent with a vascular lesion. Surgical excision was performed, and histopathological analysis confirmed a venous-type synovial haemangioma, characterized by large-calibre vascular channels lined by bland endothelial cells and containing organizing thrombi. The postoperative course was uneventful, and the patient remained disease-free at 6 months of follow-up. Conclusion Synovial haemangioma, though rare, should be considered in the differential diagnosis of recurrent knee effusions in young patients. It may mimic other benign or malignant periarticular lesions. MRI plays a key role in the evaluation, and the diagnosis can be strongly suggested by imaging, but histopathological confirmation remains essential for accurate characterization and appropriate management.

International Journal of Surgical Pathology
Hospital Universitario La Paz (ES), Hospital General Universitario Gregorio Marañón (ES), Universidad Nuestra Señora de La Paz (BO), Hospital Nuestra Señora de Alarcos (ES)
Good health and well-being
Openalex Percentile: Top 10%
Musculoskeletal synovial abnormalities and treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.