Gout: Contemporary Approaches to Diagnosis, Treatment, and Long-Term Management

This narrative review summarizes contemporary approaches to the diagnosis, treatment, and long-term management of gout. It discusses pathogenesis, clinical presentation, diagnostic methods, management of acute gout flares, urate-lowering therapy, treat-to-target strategies, lifestyle and comorbidity management, and rehabilitation. Particular emphasis is placed on achieving sustained serum urate control, preventing recurrent flares, reducing crystal burden, and preserving joint function.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-09-18
DOI
https://doi.org/10.5281/zenodo.22830255
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
preprint
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preprint

Gout: Contemporary Approaches to Diagnosis, Treatment, and Long-Term Management

Irakli Shelia
Zenodo (CERN European Organization for Nuclear Research)
Gout, Hyperuricemia, Uric Acid
preprint

Gout: Contemporary Approaches to Diagnosis, Treatment, and Long-Term Management

Irakli Shelia
preprint en

Abstract

This narrative review summarizes contemporary approaches to the diagnosis, treatment, and long-term management of gout. It discusses pathogenesis, clinical presentation, diagnostic methods, management of acute gout flares, urate-lowering therapy, treat-to-target strategies, lifestyle and comorbidity management, and rehabilitation. Particular emphasis is placed on achieving sustained serum urate control, preventing recurrent flares, reducing crystal burden, and preserving joint function.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Gout, Hyperuricemia, Uric Acid
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Gout: Contemporary Approaches to Diagnosis, Treatment, and Long-Term Management — Irakli Shelia · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS