Allergic rhinitis in primary care: Navigating diagnostic uncertainty, treatment failure and referral

Abstract Allergic rhinitis is usually first recognised and treated in primary care, where decisions often precede allergen testing or specialist assessment. The challenge is not simply identifying classic allergic symptoms, but distinguishing clinically relevant allergy from sensitisation, nonallergic rhinitis, chronic rhinosinusitis and structural disease; selecting treatment according to burden; and recognising when apparent treatment failure reflects poor adherence, incorrect intranasal spray technique or an alternative diagnosis. This practice-oriented Review translates current guideline and consensus evidence into a decision sequence for first-contact care. It focuses on when a clinical diagnosis is sufficient, when targeted skin-prick or serum allergen-specific IgE testing will change management, how to optimise intranasal treatment, and how to separate allergy/immunology from otolaryngology referral pathways. The aim is to reduce indiscriminate testing, unnecessary treatment escalation and delayed referral while preserving the longitudinal advantages of primary care.

Authors

Institutions

Publication Details

Journal
npj Primary Care Respiratory Medicine
Published
2026-09-18
DOI
https://doi.org/10.1038/s41533-026-00563-w
Primary Topic
Allergic Rhinitis and Sensitization
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Allergic rhinitis in primary care: Navigating diagnostic uncertainty, treatment failure and referral

Ece Çelik
npj Primary Care Respiratory Medicine
Allergic Rhinitis and Sensitization
article

Allergic rhinitis in primary care: Navigating diagnostic uncertainty, treatment failure and referral

Ece Çelik
article en

Abstract

Abstract Allergic rhinitis is usually first recognised and treated in primary care, where decisions often precede allergen testing or specialist assessment. The challenge is not simply identifying classic allergic symptoms, but distinguishing clinically relevant allergy from sensitisation, nonallergic rhinitis, chronic rhinosinusitis and structural disease; selecting treatment according to burden; and recognising when apparent treatment failure reflects poor adherence, incorrect intranasal spray technique or an alternative diagnosis. This practice-oriented Review translates current guideline and consensus evidence into a decision sequence for first-contact care. It focuses on when a clinical diagnosis is sufficient, when targeted skin-prick or serum allergen-specific IgE testing will change management, how to optimise intranasal treatment, and how to separate allergy/immunology from otolaryngology referral pathways. The aim is to reduce indiscriminate testing, unnecessary treatment escalation and delayed referral while preserving the longitudinal advantages of primary care.

npj Primary Care Respiratory Medicine
Trakya University (TR)
Openalex Percentile: Top 14%
Allergic Rhinitis and Sensitization
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Allergic rhinitis in primary care: Navigating diagnostic uncertainty, treatment failure and referral — Ece Çelik · npj Primary Care Respiratory Medicine (2026) | TGRS Research Map | TGRS