The right inferior parietal lobule in spaceflight adaptation: a review of gravity-related processing mechanisms

Spaceflight alters vestibular and multisensory processing, requiring adaptation to reduced gravitational input. This review examines evidence for the involvement of the right inferior parietal lobule in altered-gravity adaptation, focusing on the supramarginal gyrus, angular gyrus, and intraparietal sulcus. Current evidence is consistent with right parietal involvement in spatial orientation, sensory reweighting, and internal-model updating, but does not yet establish region-specific or causal mechanisms. Future multimodal studies are needed to test these proposed functions and clarify causal roles.