Window within the web: Bilateral florid persistent pupillary membranes

A 14-year-old boy was found to have bilateral persistent pupillary membranes with best-corrected visual acuity of 6/6 in both eyes. (A, B) Diffuse slit-lamp photographs of the right and left eyes show extensive pigmented pupillary membrane strands arising from the iris collarette and interlacing across the pupillary apertures, producing a dense web-like configuration with multiple irregular fenestrations. (C, D) Retroillumination sharply delineates the membrane architecture against the red reflex, revealing residual optical windows, including clear openings along the visual axis. Despite the florid appearance of the membranes, preservation of these central optical windows likely accounts for the excellent visual acuity. The panels highlight a striking anatomy-function dissociation in which a dense pupillary web retains sufficient optical windows for excellent vision.

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Publication Details

Journal
European Journal of Ophthalmology
Published
2026-09-18
DOI
https://doi.org/10.1177/11206721261489699
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
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article

Window within the web: Bilateral florid persistent pupillary membranes

E Rajesh, Shanmathi Thiyagarajan, Elackiya Manimaran
European Journal of Ophthalmology
Glaucoma and retinal disorders
article

Window within the web: Bilateral florid persistent pupillary membranes

E Rajesh, Shanmathi Thiyagarajan, Elackiya Manimaran
article en

Abstract

A 14-year-old boy was found to have bilateral persistent pupillary membranes with best-corrected visual acuity of 6/6 in both eyes. (A, B) Diffuse slit-lamp photographs of the right and left eyes show extensive pigmented pupillary membrane strands arising from the iris collarette and interlacing across the pupillary apertures, producing a dense web-like configuration with multiple irregular fenestrations. (C, D) Retroillumination sharply delineates the membrane architecture against the red reflex, revealing residual optical windows, including clear openings along the visual axis. Despite the florid appearance of the membranes, preservation of these central optical windows likely accounts for the excellent visual acuity. The panels highlight a striking anatomy-function dissociation in which a dense pupillary web retains sufficient optical windows for excellent vision.

European Journal of Ophthalmology
Aravind Eye Hospital (IN), Institute of Ophthalmology (MX)
Openalex Percentile: Top 8%
Glaucoma and retinal disorders
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Window within the web: Bilateral florid persistent pupillary membranes — E Rajesh, Shanmathi Thiyagarajan, et al. · European Journal of Ophthalmology (2026) | TGRS Research Map | TGRS