Application of Tikhonov's theory to an age-structured singularly perturbed SIS model with a general treatment function

We consider a simple SIS model with a general nonlinear treatment function. We combine it with a demographic model, keeping in mind the difference in time scale. A slow-fast system emerges. Our purpose is to show how Tikhonov's Theorem for singularly perturbed systems can be applied to reduce the whole model to planar systems that approximate its slow phases. Based on assumptions made about the treatment function, we determine graphically the number and the attractivity of slow surfaces on which reduced problems are defined. Approximation results are given on bounded, arbitrarily large and unbounded time intervals. An example is examined for a function that combines a natural recovery rate and a homographic treatment function that takes into account the limitations of hospital capacities. Numerical simulations are interpreted in light of theoretical results, followed by a discussion of treatment effectiveness and healthcare capacity.

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Publication Details

Journal
Journal of Biological Systems
Published
2026-09-18
DOI
https://doi.org/10.1142/s0218339026500385
Primary Topic
Mathematical and Theoretical Epidemiology and Ecology Models
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article
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article

Application of Tikhonov's theory to an age-structured singularly perturbed SIS model with a general treatment function

Karim Yadi, Radhwane Benkhaled
Journal of Biological Systems
Mathematical and Theoretical Epidemiology and Ecology Models
article

Application of Tikhonov's theory to an age-structured singularly perturbed SIS model with a general treatment function

Karim Yadi, Radhwane Benkhaled
article en

Abstract

We consider a simple SIS model with a general nonlinear treatment function. We combine it with a demographic model, keeping in mind the difference in time scale. A slow-fast system emerges. Our purpose is to show how Tikhonov's Theorem for singularly perturbed systems can be applied to reduce the whole model to planar systems that approximate its slow phases. Based on assumptions made about the treatment function, we determine graphically the number and the attractivity of slow surfaces on which reduced problems are defined. Approximation results are given on bounded, arbitrarily large and unbounded time intervals. An example is examined for a function that combines a natural recovery rate and a homographic treatment function that takes into account the limitations of hospital capacities. Numerical simulations are interpreted in light of theoretical results, followed by a discussion of treatment effectiveness and healthcare capacity.

Journal of Biological Systems
Twitter (United States) (US)
Good health and well-being
Openalex Percentile: Top 9%
Mathematical and Theoretical Epidemiology and Ecology Models
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Application of Tikhonov's theory to an age-structured singularly perturbed SIS model with a general treatment function — Karim Yadi, Radhwane Benkhaled · Journal of Biological Systems (2026) | TGRS Research Map | TGRS