A population representative XAI framework for transparent dysglycemia screening in Indonesia

Deploying trustworthy AI requires more than predictive accuracy; it demands population-representative data, transparent explainability, and user-centered design. Despite rapid mobile penetration across Southeast Asia, existing AI-based health tools remain predominantly trained on non-representative datasets and function as opaque black-box systems, limiting clinical trust. This study addresses these gaps through a deployable Explainable AI (XAI) framework for dysglycemia screening in Indonesia. Features were extracted from the Indonesia Family Life Survey 5 (IFLS5), a nationally representative longitudinal survey ( $$\\sim $$ 83% of the Indonesian population), using its measured HbA1c-based labels for dysglycemia screening. Feature selection employed a four-stage XAI-in-the-loop pipeline combining literature review, statistical filtering, domain expert consultation, and SHAP-based evaluation. Among models trained, XGBoost achieved the highest performance (ROC-AUC = 0.72), with SHAP used both for post-hoc interpretation and feature selection. SHAP analysis indicated clinical alignment, with age, BMI, and hypertension as dominant risk factors, including a non-linear risk increase after age 45. The model was deployed as an Android application combining visual SHAP explanations with LLM-generated narratives. A pilot evaluation (n = 12) returned a mean comprehension score of 4.31/5. The framework illustrates an approach for developing transparent, population-representative mHealth AI that is meaningful and accessible to its intended users.

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Publication Details

Journal
Discover Artificial Intelligence
Published
2026-09-18
DOI
https://doi.org/10.1007/s44163-026-02243-7
Primary Topic
Machine Learning in Healthcare
Type
article
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A population representative XAI framework for transparent dysglycemia screening in Indonesia

Hidetaka Nambo, Latifa Dwiyanti, Henry Anand Septian Radityo, Bernardus Willson et al.
Discover Artificial Intelligence
Machine Learning in Healthcare
article

A population representative XAI framework for transparent dysglycemia screening in Indonesia

Hidetaka Nambo, Latifa Dwiyanti, Henry Anand Septian Radityo, Bernardus Willson, Saiful Akbar, Raynard Tanadi
article en

Abstract

Deploying trustworthy AI requires more than predictive accuracy; it demands population-representative data, transparent explainability, and user-centered design. Despite rapid mobile penetration across Southeast Asia, existing AI-based health tools remain predominantly trained on non-representative datasets and function as opaque black-box systems, limiting clinical trust. This study addresses these gaps through a deployable Explainable AI (XAI) framework for dysglycemia screening in Indonesia. Features were extracted from the Indonesia Family Life Survey 5 (IFLS5), a nationally representative longitudinal survey ( $$\sim $$ 83% of the Indonesian population), using its measured HbA1c-based labels for dysglycemia screening. Feature selection employed a four-stage XAI-in-the-loop pipeline combining literature review, statistical filtering, domain expert consultation, and SHAP-based evaluation. Among models trained, XGBoost achieved the highest performance (ROC-AUC = 0.72), with SHAP used both for post-hoc interpretation and feature selection. SHAP analysis indicated clinical alignment, with age, BMI, and hypertension as dominant risk factors, including a non-linear risk increase after age 45. The model was deployed as an Android application combining visual SHAP explanations with LLM-generated narratives. A pilot evaluation (n = 12) returned a mean comprehension score of 4.31/5. The framework illustrates an approach for developing transparent, population-representative mHealth AI that is meaningful and accessible to its intended users.

Discover Artificial IntelligenceVol. 6(1)
Kanazawa University (JP), Bandung Institute of Technology (ID)
Partnerships for the goals
Openalex Percentile: Top 9%
Machine Learning in Healthcare
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A population representative XAI framework for transparent dysglycemia screening in Indonesia — Hidetaka Nambo, Latifa Dwiyanti, et al. · Discover Artificial Intelligence (2026) | TGRS Research Map | TGRS