A population representative XAI framework for transparent dysglycemia screening in Indonesia
Deploying trustworthy AI requires more than predictive accuracy; it demands population-representative data, transparent explainability, and user-centered design. Despite rapid mobile penetration across Southeast Asia, existing AI-based health tools remain predominantly trained on non-representative datasets and function as opaque black-box systems, limiting clinical trust. This study addresses these gaps through a deployable Explainable AI (XAI) framework for dysglycemia screening in Indonesia. Features were extracted from the Indonesia Family Life Survey 5 (IFLS5), a nationally representative longitudinal survey ( $$\\sim $$ 83% of the Indonesian population), using its measured HbA1c-based labels for dysglycemia screening. Feature selection employed a four-stage XAI-in-the-loop pipeline combining literature review, statistical filtering, domain expert consultation, and SHAP-based evaluation. Among models trained, XGBoost achieved the highest performance (ROC-AUC = 0.72), with SHAP used both for post-hoc interpretation and feature selection. SHAP analysis indicated clinical alignment, with age, BMI, and hypertension as dominant risk factors, including a non-linear risk increase after age 45. The model was deployed as an Android application combining visual SHAP explanations with LLM-generated narratives. A pilot evaluation (n = 12) returned a mean comprehension score of 4.31/5. The framework illustrates an approach for developing transparent, population-representative mHealth AI that is meaningful and accessible to its intended users.
Authors
- Hidetaka Nambo (ORCID: https://orcid.org/0000-0003-4223-6145)
- Latifa Dwiyanti (ORCID: https://orcid.org/0000-0002-4848-1590)
- Henry Anand Septian Radityo
- Bernardus Willson
- Saiful Akbar
- Raynard Tanadi
Institutions
- Kanazawa University (JP)
- Bandung Institute of Technology (ID)
Publication Details
- Journal
- Discover Artificial Intelligence
- Published
- 2026-09-18
- DOI
- https://doi.org/10.1007/s44163-026-02243-7
- Primary Topic
- Machine Learning in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00