Limitations of PIV Biomarker Analysis Related to Chemoradiotherapy and Unadjusted Confounders

The pan-immune-inflammation value (PIV) derived from four blood cell counts warrants cautious interpretation in rectal-cancer immunotherapy, as CRT cannot be disentangled from anti-PD-1 effects within the small n = 16 subgroup.

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Publication Details

Journal
Cancer Science
Published
2026-09-17
DOI
https://doi.org/10.1111/cas.70543
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
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article

Limitations of PIV Biomarker Analysis Related to Chemoradiotherapy and Unadjusted Confounders

Wencai Weng, Hongbo Gao
Cancer Science
Inflammatory Biomarkers in Disease Prognosis
article

Limitations of PIV Biomarker Analysis Related to Chemoradiotherapy and Unadjusted Confounders

Wencai Weng, Hongbo Gao
article en

Abstract

The pan-immune-inflammation value (PIV) derived from four blood cell counts warrants cautious interpretation in rectal-cancer immunotherapy, as CRT cannot be disentangled from anti-PD-1 effects within the small n = 16 subgroup.

Cancer Science
Affiliated Zhongshan Hospital of Dalian University (CN)
Good health and well-being
Openalex Percentile: Top 14%
Inflammatory Biomarkers in Disease Prognosis
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Limitations of PIV Biomarker Analysis Related to Chemoradiotherapy and Unadjusted Confounders — Wencai Weng, Hongbo Gao · Cancer Science (2026) | TGRS Research Map | TGRS