A waste audit on different nebulization practices to treat respiratory conditions in the ICU

BACKGROUND: Aerosolized medications are frequently administered through nebulization to treat respiratory conditions. Vibrating mesh nebulizers (VMN) are preferred over junction emission technology (JET) nebulizers (JN) in providing effective treatment. They potentially differ in environmental impact due to differences in product and medicine waste. AIM: To quantify waste related to nebulization by JN and VMN to determine the most sustainable nebulization option in the ICU. METHODS: A waste audit was performed in the ICU of Erasmus University Medical Center, Rotterdam, The Netherlands. The functional unit was product waste per nebulization, cumulative waste generated by nebulization over nine days and product waste in one year. Waste of two JN and two VMN was quantified, including packaging and administration products. Nebulization was simulated to determine medication waste per nebulizer. Total amount of waste was calculated per nebulization and extrapolated for the year 2023. RESULTS: Overall, JN generated more waste than VMN. VMN in non-mechanically ventilated patients without tracheostomy generated more waste compared to JN on day one. Use beyond one day resulted in more waste for JN compared to VMN, related to product waste. Additionally, medication waste differed between JN (median of 0.60 mL) and VMN (median of 0.06 mL). Based on 2230 nebulizations in the ICU in 2023, JN produced 91,1 kg of waste and VMN produced 35,4 kg of waste. CONCLUSION: Nebulization with VMN generated less product and medication waste than JN in the ICU. VMN may therefore be a more sustainable option for treating acute respiratory conditions in the ICU.

Authors

Institutions

Publication Details

Journal
Journal of Critical Care
Published
2026-09-17
DOI
https://doi.org/10.1016/j.jcrc.2026.155744
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

A waste audit on different nebulization practices to treat respiratory conditions in the ICU

Karenin van Grafhorst, Nicole Hunfeld, Lisa-Marie Smale, Nico Goedendorp
Journal of Critical Care
Inhalation and Respiratory Drug Delivery
article

A waste audit on different nebulization practices to treat respiratory conditions in the ICU

Karenin van Grafhorst, Nicole Hunfeld, Lisa-Marie Smale, Nico Goedendorp
article en

Abstract

BACKGROUND: Aerosolized medications are frequently administered through nebulization to treat respiratory conditions. Vibrating mesh nebulizers (VMN) are preferred over junction emission technology (JET) nebulizers (JN) in providing effective treatment. They potentially differ in environmental impact due to differences in product and medicine waste. AIM: To quantify waste related to nebulization by JN and VMN to determine the most sustainable nebulization option in the ICU. METHODS: A waste audit was performed in the ICU of Erasmus University Medical Center, Rotterdam, The Netherlands. The functional unit was product waste per nebulization, cumulative waste generated by nebulization over nine days and product waste in one year. Waste of two JN and two VMN was quantified, including packaging and administration products. Nebulization was simulated to determine medication waste per nebulizer. Total amount of waste was calculated per nebulization and extrapolated for the year 2023. RESULTS: Overall, JN generated more waste than VMN. VMN in non-mechanically ventilated patients without tracheostomy generated more waste compared to JN on day one. Use beyond one day resulted in more waste for JN compared to VMN, related to product waste. Additionally, medication waste differed between JN (median of 0.60 mL) and VMN (median of 0.06 mL). Based on 2230 nebulizations in the ICU in 2023, JN produced 91,1 kg of waste and VMN produced 35,4 kg of waste. CONCLUSION: Nebulization with VMN generated less product and medication waste than JN in the ICU. VMN may therefore be a more sustainable option for treating acute respiratory conditions in the ICU.

Journal of Critical CareVol. 97
Erasmus MC (NL), Erasmus University Rotterdam (NL)
Clean water and sanitation
Openalex Percentile: Top 11%
Inhalation and Respiratory Drug Delivery
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

A waste audit on different nebulization practices to treat respiratory conditions in the ICU — Karenin van Grafhorst, Nicole Hunfeld, et al. · Journal of Critical Care (2026) | TGRS Research Map | TGRS