Antibodies against HLA-E-VL9 enhance NK cell and CD8+ T cell cytotoxicity against tumor cells and HIV-infected CD4+ T cells.

T cell function and by promoting ADCC.

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Publication Details

Journal
PubMed
Published
2026-09-16
DOI
https://doi.org/10.1126/scitranslmed.aea3879
Primary Topic
Immune Cell Function and Interaction
Type
article
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article

Antibodies against HLA-E-VL9 enhance NK cell and CD8+ T cell cytotoxicity against tumor cells and HIV-infected CD4+ T cells.

Hongbing Yang, A. Brenda Kapingidza, Daniel J. Marston, Brianna Rhodes et al.
PubMed
Immune Cell Function and Interaction
article

Antibodies against HLA-E-VL9 enhance NK cell and CD8+ T cell cytotoxicity against tumor cells and HIV-infected CD4+ T cells.

Hongbing Yang, A. Brenda Kapingidza, Daniel J. Marston, Brianna Rhodes, Persephone Borrow, Marina Tuyishime, Daniel Wrapp, Simon Brackenridge, Anna E. Kliszczak, Caitlin Harris, Jacob Gater, McKenzie Frazier, Barton F Haynes, Guido Ferrari, Andrew J McMichael, Mihai L Azoitei, Richard Scearce, Max Quastel, Dapeng Li, Nicholas P Levering, Joyce K Hwang, Geraldine M Gillespie
article en

Abstract

No abstract available for this paper.

PubMedVol. 18(867)
Duke University (US), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), University of Oxford (GB)
Good health and well-being
Openalex Percentile: Top 17%
Immune Cell Function and Interaction
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Antibodies against HLA-E-VL9 enhance NK cell and CD8+ T cell cytotoxicity against tumor cells and HIV-infected CD4+ T cells. — Hongbing Yang, A. Brenda Kapingidza, et al. · PubMed (2026) | TGRS Research Map | TGRS