Global Equity in Alzheimer's Disease and Cancer Clinical Research: Trial Representation Dataset, TREI-AC Scoring Code, and Supporting Documentation

This deposit contains the original dataset, coding and scoring scripts, and methodology documents underlying a monograph on global equity in Alzheimer's disease and cancer clinical research. It includes 400 randomly sampled interventional trials (200 per disease) drawn from ClinicalTrials.gov, coded against a six-category exclusion-criteria taxonomy and merged with World Bank income-tier classifications; domain and composite scores from TREI-AC, an Alzheimer's/cancer adaptation of the Trial Representation Equity Index (TREI, DOI: 10.5281/zenodo.21539926); a dedicated, exhaustive pull of all India-sited interventional trials for both diseases; the 30-trial stratified sample used for coding validation; and all Python scripts used to generate, code, and score this dataset, including an independent re-implementation used to verify the scoring logic. Also included is the command-line companion to Lexis, a browser-based keyword comparison tool developed as part of this research (https://macaly-cumrqk2asnom26x13s972t12-prod.macaly-app.com). Full file descriptions are in README.md.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-09-16
DOI
https://doi.org/10.5281/zenodo.22799082
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
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Global Equity in Alzheimer's Disease and Cancer Clinical Research: Trial Representation Dataset, TREI-AC Scoring Code, and Supporting Documentation

Khan Gulrez Shagufa Fazal Ahmed
Zenodo (CERN European Organization for Nuclear Research)
Dementia and Cognitive Impairment Research
article

Global Equity in Alzheimer's Disease and Cancer Clinical Research: Trial Representation Dataset, TREI-AC Scoring Code, and Supporting Documentation

Khan Gulrez Shagufa Fazal Ahmed
article en

Abstract

This deposit contains the original dataset, coding and scoring scripts, and methodology documents underlying a monograph on global equity in Alzheimer's disease and cancer clinical research. It includes 400 randomly sampled interventional trials (200 per disease) drawn from ClinicalTrials.gov, coded against a six-category exclusion-criteria taxonomy and merged with World Bank income-tier classifications; domain and composite scores from TREI-AC, an Alzheimer's/cancer adaptation of the Trial Representation Equity Index (TREI, DOI: 10.5281/zenodo.21539926); a dedicated, exhaustive pull of all India-sited interventional trials for both diseases; the 30-trial stratified sample used for coding validation; and all Python scripts used to generate, code, and score this dataset, including an independent re-implementation used to verify the scoring logic. Also included is the command-line companion to Lexis, a browser-based keyword comparison tool developed as part of this research (https://macaly-cumrqk2asnom26x13s972t12-prod.macaly-app.com). Full file descriptions are in README.md.

Zenodo (CERN European Organization for Nuclear Research)
Reduced inequalities
Openalex Percentile: Top 10%
Dementia and Cognitive Impairment Research
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Global Equity in Alzheimer's Disease and Cancer Clinical Research: Trial Representation Dataset, TREI-AC Scoring Code, and Supporting Documentation — Khan Gulrez Shagufa Fazal Ahmed · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS