Autonomic control of aquaporin-4–dependent perivascular clearance and iron retention: a candidate determinant of lesion topography and pre-clinical timing in multiple sclerosis

This is Version 2 (v2) of this preprint. It supersedes v1 and incorporates substantive editorial revisions, completed reference citations, updated bibliographic details, and clarification of the proposed mechanistic framework and testable predictions. The core hypothesis remains unchanged.