Fractal Colonization of Prebiotic Niches: Mechanical Budding of Nanovesicles and Kinetic Resource Depletion as an Oncological Atavism

This article extends the geo-biomimetic dissipative theory of abiogenesis, focusing on a purely physical mechanism of prebiotic resource competition and the colonization of the early Earth. While classical models consider protocell replication solely through symmetric fission, this work proposes a model of fractal membrane budding (blebbing) induced by hydrodynamic shear stress from Kármán vortices. Through the numerical solution of a system of differential equations in a Python environment, we demonstrate that a macroscopic mother vesicle , 20 micron subjected to periodic pulses 1 Hz, rhythmically generates sub-microscopic nanovesicles okolo (100 nm) that act as environmental probes.Our coupled model of mass transport and chemical kinetics reveals that the resulting nanovesicles exhibit a diffusion coefficient orders of magnitude higher due to their size, enabling them to rapidly migrate into protected micro-capillaries and low-flow sediments. Within these niches, the nanoprobes begin to passively bind and integrate free fatty acids (FFAs); in the simulation plot, this manifests as a discrete, stepwise decline in the local concentration of free resources, synchronized with the mechanical peaks of the planetary oscillator. This process operates purely on the basis of thermodynamic stability (DKS), independent of protein regulation, and traps free energy via a so-called molecular trap.We propose the groundbreaking hypothesis that this mechanism represents a direct evolutionary equivalent to the atavistic transport processes of modern cancer cells, which utilize extracellular vesicles (ECVs/exosomes) to selectively deprive healthy tissues of nutrients and establish pre-metastatic niches. Simulation results confirm that the selfish physical competition for resources and the driven occupation of space are fundamental, intrinsic properties of physical life—traits that had to be subsequently suppressed by modern biochemical regulatory mechanisms during the emergence of multicellularity. The study thus establishes a new bridge between prebiotic hydrodynamics and biophysical oncology.