CLINICAL EVALUATION OF YASTHIMADHU GHRITA PRATISARANA IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS (OSMF): A CASE REPORT

Background: Oral Submucous Fibrosis (OSMF) is a chronic, progressive, debilitating, and potentially malignant disorder of the oral cavity characterized by juxta-epithelial inflammatory changes followed by progressive fibrosis of the lamina propria and deeper connective tissues. The disease results in reduced mouth opening, burning sensation, intolerance to spicy food, impaired mastication, and deterioration in the patient's quality of life. Habitual chewing of areca nut and commercially available preparations such as gutkha and pan masala remains the principal etiological factor, particularly in the Indian subcontinent.[1-3] Despite numerous available treatment modalities, long-term therapeutic outcomes remain inconsistent, and recurrence is common. Ayurveda emphasizes disease management through correction of the underlying pathological process rather than symptomatic relief alone.

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Publication Details

Journal
World Journal of Pharmaceutical Research
Published
2026-09-17
DOI
https://doi.org/10.5281/zenodo.22811083
Primary Topic
Oral Health Pathology and Treatment
Type
article
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article

CLINICAL EVALUATION OF YASTHIMADHU GHRITA PRATISARANA IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS (OSMF): A CASE REPORT

Siva Kumar C. S.2 Dr. Ankit Sharma*1
World Journal of Pharmaceutical Research
Oral Health Pathology and Treatment
article

CLINICAL EVALUATION OF YASTHIMADHU GHRITA PRATISARANA IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS (OSMF): A CASE REPORT

Siva Kumar C. S.2 Dr. Ankit Sharma*1
article en

Abstract

Background: Oral Submucous Fibrosis (OSMF) is a chronic, progressive, debilitating, and potentially malignant disorder of the oral cavity characterized by juxta-epithelial inflammatory changes followed by progressive fibrosis of the lamina propria and deeper connective tissues. The disease results in reduced mouth opening, burning sensation, intolerance to spicy food, impaired mastication, and deterioration in the patient's quality of life. Habitual chewing of areca nut and commercially available preparations such as gutkha and pan masala remains the principal etiological factor, particularly in the Indian subcontinent.[1-3] Despite numerous available treatment modalities, long-term therapeutic outcomes remain inconsistent, and recurrence is common. Ayurveda emphasizes disease management through correction of the underlying pathological process rather than symptomatic relief alone.

World Journal of Pharmaceutical Research
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Oral Health Pathology and Treatment
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CLINICAL EVALUATION OF YASTHIMADHU GHRITA PRATISARANA IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS (OSMF): A CASE REPORT — Siva Kumar C. S.2 Dr. Ankit Sharma*1 · World Journal of Pharmaceutical Research (2026) | TGRS Research Map | TGRS