Circulating Surfactant Proteins B and D are associated with Interstitial Lung Abnormalities and their Progression
Extract Interstitial lung abnormalities (ILA) are incidental CT findings, characterised by non-dependent parenchymal abnormalities -as ground-glass opacities, reticulation, and traction bronchiectasis- affecting at least 5% of a lung zone [1]. Their detection is increasing with widespread CT use in e.g. cancer screening and cardiovascular diagnostic imaging. Prevalence ranges from 2 to 35%, occurring commonly in older individuals, smokers, and those with a family history of interstitial lung disease (ILD).
Authors
- Pim A. de Jong (ORCID: https://orcid.org/0000-0003-4840-6854)
- Anke H. Maitland‐van der Zee (ORCID: https://orcid.org/0000-0002-0414-3442)
- Firdaus A. A. Mohamed Hoesein (ORCID: https://orcid.org/0000-0003-2536-9384)
- Esther J. Nossent (ORCID: https://orcid.org/0000-0003-3854-4137)
- Mark A. van de Wiel (ORCID: https://orcid.org/0000-0003-4780-8472)
- JanWillem Duitman (ORCID: https://orcid.org/0000-0003-4254-3380)
- Harry J.M. Groen (ORCID: https://orcid.org/0000-0002-2978-5265)
- Esther Pompe (ORCID: https://orcid.org/0000-0002-1749-0208)
- Iris A. Simons (ORCID: https://orcid.org/0009-0007-9686-3167)
Institutions
- University Medical Center Groningen (NL)
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2026-09-17
- DOI
- https://doi.org/10.1183/23120541.00623-2026
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00