Research on Optimization and Performance Analysis of Centrifugal Blood Pump Blade Parameters Based on Numerical Simulation

OBJECTIVE: Taking the centrifugal blood pump as the research object, this study investigates the effects of blade type and blade wrap angle on pump performance, aiming to determine the optimal blade configuration and the appropriate range of the correlation coefficient φ = zψ/360° for low-specific-speed centrifugal blood pumps. METHODS: The impeller of the centrifugal blood pump was designed using the velocity coefficient method. Computational fluid dynamics (CFD) simulations were performed to evaluate pump performance. The Eulerian hemolysis estimation model was employed to compare the effects of cylindrical blades with different wrap angles and twisted blades on key performance indicators, including the hemolysis index. RESULTS: The designed centrifugal blood pump meets the normal physiological requirements of adults and exhibits good blood compatibility. At the design flow rate, twisted blades provide higher pressure head and hydraulic efficiency than cylindrical blades, but at the cost of increased blood damage. For a six-blade centrifugal blood pump with a specific speed of 70, the optimal wrap angle range that balances hydraulic performance and hemolysis is 90°-110°, corresponding to a correlation coefficient f ranging from 1.5 to 1.8. CONCLUSION: The cylindrical blade impeller demonstrates better hemolysis performance at the design flow rate. The identified optimal range of the correlation coefficient f extends an established industrial pump correlation to the field of centrifugal blood pumps, providing a valuable design reference for future blood pump development.

Authors

Institutions

Publication Details

Journal
Journal of Biomechanical Engineering
Published
2026-09-17
DOI
https://doi.org/10.1115/1.4072711
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Research on Optimization and Performance Analysis of Centrifugal Blood Pump Blade Parameters Based on Numerical Simulation

Wen Xu, Hui Song, cheng-cheng Li, Ying Wang et al.
Journal of Biomechanical Engineering
Mechanical Circulatory Support Devices
article

Research on Optimization and Performance Analysis of Centrifugal Blood Pump Blade Parameters Based on Numerical Simulation

Wen Xu, Hui Song, cheng-cheng Li, Ying Wang, Jianying Ma
article en

Abstract

OBJECTIVE: Taking the centrifugal blood pump as the research object, this study investigates the effects of blade type and blade wrap angle on pump performance, aiming to determine the optimal blade configuration and the appropriate range of the correlation coefficient φ = zψ/360° for low-specific-speed centrifugal blood pumps. METHODS: The impeller of the centrifugal blood pump was designed using the velocity coefficient method. Computational fluid dynamics (CFD) simulations were performed to evaluate pump performance. The Eulerian hemolysis estimation model was employed to compare the effects of cylindrical blades with different wrap angles and twisted blades on key performance indicators, including the hemolysis index. RESULTS: The designed centrifugal blood pump meets the normal physiological requirements of adults and exhibits good blood compatibility. At the design flow rate, twisted blades provide higher pressure head and hydraulic efficiency than cylindrical blades, but at the cost of increased blood damage. For a six-blade centrifugal blood pump with a specific speed of 70, the optimal wrap angle range that balances hydraulic performance and hemolysis is 90°-110°, corresponding to a correlation coefficient f ranging from 1.5 to 1.8. CONCLUSION: The cylindrical blade impeller demonstrates better hemolysis performance at the design flow rate. The identified optimal range of the correlation coefficient f extends an established industrial pump correlation to the field of centrifugal blood pumps, providing a valuable design reference for future blood pump development.

Journal of Biomechanical Engineering
University of Shanghai for Science and Technology (CN), Shanghai University of Electric Power (CN), Fudan University (CN), Zhongshan Hospital (CN)
Affordable and clean energy
Openalex Percentile: Top 21%
Mechanical Circulatory Support Devices
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Research on Optimization and Performance Analysis of Centrifugal Blood Pump Blade Parameters Based on Numerical Simulation — Wen Xu, Hui Song, et al. · Journal of Biomechanical Engineering (2026) | TGRS Research Map | TGRS