Human Adenovirus B3–Induced Immune Thrombocytopenia and Thrombosis

Virus-induced immune thrombocytopenia and thrombosis after HAdV-B3 infection supports a shared platelet factor 4–targeted immune mechanism linking natural adenovirus infection and adenoviral vector–associated disease.

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Publication Details

Journal
New England Journal of Medicine
Published
2026-09-16
DOI
https://doi.org/10.1056/nejmc2605960
Primary Topic
Parvovirus B19 Infection Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Human Adenovirus B3–Induced Immune Thrombocytopenia and Thrombosis

Thomas Thiele, Wibke Bayer, Werner Streif, Christian Irsara et al.
New England Journal of Medicine
Parvovirus B19 Infection Studies
article

Human Adenovirus B3–Induced Immune Thrombocytopenia and Thrombosis

Thomas Thiele, Wibke Bayer, Werner Streif, Christian Irsara, Linda Schönborn, Markus Anliker, Andreas Greinacher, Lorin Loacker, Andrea Griesmacher, Alex Moser, Xiaoyan Wang, Christoph Winkler, Thomas Müller, Habib Benainouna, Jing Jing Wang
article en

Abstract

Virus-induced immune thrombocytopenia and thrombosis after HAdV-B3 infection supports a shared platelet factor 4–targeted immune mechanism linking natural adenovirus infection and adenoviral vector–associated disease.

New England Journal of MedicineVol. 395(11)
Innsbruck Medical University (AT), Flinders University (AU), Universitätsmedizin Greifswald (DE), Essen University Hospital (DE)
Bill and Melinda Gates Foundation, American Society of Hematology, Deutsche Forschungsgemeinschaft, Else Kröner-Fresenius-Stiftung, Flinders Foundation, National Health and Medical Research Council
Zero hunger
Openalex Percentile: Top 11%
Parvovirus B19 Infection Studies
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Human Adenovirus B3–Induced Immune Thrombocytopenia and Thrombosis — Thomas Thiele, Wibke Bayer, et al. · New England Journal of Medicine (2026) | TGRS Research Map | TGRS