Multiple HRAS Hot-Spot Somatic Variations in a Patient With Eruptive Disseminated Spitz Nevi

This genetic profiling study investigates if eruptive disseminated Spitz nevi can arise from multiple progenitor populations and identifies 4 HRAS hot-spot somatic variations within a single patient.

Authors

Institutions

Publication Details

Journal
JAMA Dermatology
Published
2026-09-16
DOI
https://doi.org/10.1001/jamadermatol.2026.3428
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Multiple HRAS Hot-Spot Somatic Variations in a Patient With Eruptive Disseminated Spitz Nevi

Lewis J. Kirkegaard, Jamie Zussman, Douglas Grossman, Eric A. Smith et al.
JAMA Dermatology
Cutaneous Melanoma Detection and Management
article

Multiple HRAS Hot-Spot Somatic Variations in a Patient With Eruptive Disseminated Spitz Nevi

Lewis J. Kirkegaard, Jamie Zussman, Douglas Grossman, Eric A. Smith, Robert L. Judson‐Torres, Patricia A. Vitale, Dekker C. Deacon, Amanda Jiang, Kenji V. Aoki, Caroline Laggis, Anneli R. Bowen, Carly A. Becker, Abigail Florell
article en

Abstract

This genetic profiling study investigates if eruptive disseminated Spitz nevi can arise from multiple progenitor populations and identifies 4 HRAS hot-spot somatic variations within a single patient.

JAMA Dermatology
University of Hawaiʻi at Mānoa (US), University of Utah (US), Huntsman Cancer Institute (US)
Climate action
Openalex Percentile: Top 13%
Cutaneous Melanoma Detection and Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.