Turning a phage anti-defense weapon into an immunity trigger

Most bacterial immune systems raise an alarm when they sense a phage. A new study in PLOS Biology shows how type II Panoptes reverses this logic by maintaining a quiet signal and sensing infection through its sudden disappearance.

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Publication Details

Journal
PLoS Biology
Published
2026-09-16
DOI
https://doi.org/10.1371/journal.pbio.3003978
Primary Topic
Bacteriophages and microbial interactions
Type
article
Field-Weighted Citation Impact
0.00

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article

Turning a phage anti-defense weapon into an immunity trigger

Naama Aviram, Anna B. Adelstein
PLoS Biology
Bacteriophages and microbial interactions
article

Turning a phage anti-defense weapon into an immunity trigger

Naama Aviram, Anna B. Adelstein
article en

Abstract

Most bacterial immune systems raise an alarm when they sense a phage. A new study in PLOS Biology shows how type II Panoptes reverses this logic by maintaining a quiet signal and sensing infection through its sudden disappearance.

PLoS BiologyVol. 24(9)
Memorial Sloan Kettering Cancer Center (US), Kettering University (US)
National Institutes of Health, National Institute of General Medical Sciences
Openalex Percentile: Top 11%
Bacteriophages and microbial interactions
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