Genomic Analysis of CTX-M-15-Producing E. coli Colonizing a Rescued Capuchin Monkey

Abstract Illegal wild animal trade and possession represents a threat to One Health due to the pathogens exchange between wild animals and humans. We report the detection and genomic characterization of a multidrug-resistant (MDR) Escherichia coli strain (MP02) colonizing a capuchin monkey ( Sapajus sp.) rescued from illegal possession. MP02 exhibited ExPEC-related genes, harbored an IncHI2-ST1 plasmid composed of quinolones, aminoglycosides, and sulfonamides resistance genes, besides the extended-spectrum β-lactamase (ESBL)-encoding gene bla CTX-M-15 located in a conserved Tn3-like transposon. To the author’s knowledge, this is the first report and genomic analysis of a MDR bacterium isolated from an illegally traded non-human primate.

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Publication Details

Journal
EcoHealth
Published
2026-09-16
DOI
https://doi.org/10.1007/s10393-026-01842-1
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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article

Genomic Analysis of CTX-M-15-Producing E. coli Colonizing a Rescued Capuchin Monkey

Gabriel Siqueira dos Santos, Vanessa Caldeira OLIVARES, Mariana Morgado Hereny, Melissa Prosperi Peixoto et al.
EcoHealth
Antibiotic Resistance in Bacteria
article

Genomic Analysis of CTX-M-15-Producing E. coli Colonizing a Rescued Capuchin Monkey

Gabriel Siqueira dos Santos, Vanessa Caldeira OLIVARES, Mariana Morgado Hereny, Melissa Prosperi Peixoto, Marcello Schiavo Nardi, Marcos Bryan Heinemann, Felipe Almeida Lucato, Gabrielli Santana Abreu, Giovanna Silva Alves de Lima, José Soares Ferreira Neto, Sérgio de Mello Novita Teixeira
article en

Abstract

Abstract Illegal wild animal trade and possession represents a threat to One Health due to the pathogens exchange between wild animals and humans. We report the detection and genomic characterization of a multidrug-resistant (MDR) Escherichia coli strain (MP02) colonizing a capuchin monkey ( Sapajus sp.) rescued from illegal possession. MP02 exhibited ExPEC-related genes, harbored an IncHI2-ST1 plasmid composed of quinolones, aminoglycosides, and sulfonamides resistance genes, besides the extended-spectrum β-lactamase (ESBL)-encoding gene bla CTX-M-15 located in a conserved Tn3-like transposon. To the author’s knowledge, this is the first report and genomic analysis of a MDR bacterium isolated from an illegally traded non-human primate.

EcoHealth
Universidade de São Paulo (BR), Prefeitura do Município de São Paulo (BR)
Openalex Percentile: Top 19%
Antibiotic Resistance in Bacteria
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Genomic Analysis of CTX-M-15-Producing E. coli Colonizing a Rescued Capuchin Monkey — Gabriel Siqueira dos Santos, Vanessa Caldeira OLIVARES, et al. · EcoHealth (2026) | TGRS Research Map | TGRS