Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC): a technical note describing a confluence-preserving endovascular technique

Abstract Introduction Endovascular therapy is the first-line treatment for superior vena cava syndrome (SVCS), yet the optimal strategy for lesions involving the brachiocephalic vein confluence remains debated. We describe a technique for anatomical bilateral reconstruction of the anonymous confluence using covered stents, called Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC). Materials and methods All patients treated for SVCS between September 2024 and December 2025 were reviewed. CERAC was selectively applied based on anatomical and clinical considerations. Procedural characteristics, technical success, complications, and follow-up patency were assessed. Results Three out of ten patients who underwent endovascular treatment for SVCS at our institution were treated using the CERAC technique. Indications included preservation of bilateral venous access in young patients with potentially treatable malignancy ( n = 2) and emergency central venous decompression ( n = 1). Technical success was achieved in all cases, with restoration of patency of both brachiocephalic veins and the superior vena cava. Mean fluoroscopy time was 30.6 min. No immediate complications occurred. Primary stent patency was maintained during available follow-up (29–301 days; median 149 days). Discussion CERAC enables confluence-preserving bilateral reconstruction while minimizing stent overlap and maintaining favourable luminal geometry. Inspired by the Covered Endovascular Reconstruction of the Aortic Bifurcation, CERAC represents, to our knowledge, the first description of a fully covered, confluence-preserving reconstruction in this anatomical setting. Conclusion CERAC is a feasible endovascular option for selected SVCS cases involving the brachiocephalic confluence. Further studies are needed to evaluate long-term outcomes and to better define appropriate indications. Level of evidence Level V.

Authors

Institutions

Publication Details

Journal
CVIR Endovascular
Published
2026-09-15
DOI
https://doi.org/10.1186/s42155-026-00765-w
Primary Topic
Central Venous Catheters and Hemodialysis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC): a technical note describing a confluence-preserving endovascular technique

Antonio Bozzani, Ludovico Ambrosi, Pietro Quaretti, Nicola Cionfoli et al.
CVIR Endovascular
Central Venous Catheters and Hemodialysis
article

Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC): a technical note describing a confluence-preserving endovascular technique

Antonio Bozzani, Ludovico Ambrosi, Pietro Quaretti, Nicola Cionfoli, Riccardo Corti, Mauro Antonio D’Agostino
article en

Abstract

Abstract Introduction Endovascular therapy is the first-line treatment for superior vena cava syndrome (SVCS), yet the optimal strategy for lesions involving the brachiocephalic vein confluence remains debated. We describe a technique for anatomical bilateral reconstruction of the anonymous confluence using covered stents, called Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC). Materials and methods All patients treated for SVCS between September 2024 and December 2025 were reviewed. CERAC was selectively applied based on anatomical and clinical considerations. Procedural characteristics, technical success, complications, and follow-up patency were assessed. Results Three out of ten patients who underwent endovascular treatment for SVCS at our institution were treated using the CERAC technique. Indications included preservation of bilateral venous access in young patients with potentially treatable malignancy ( n = 2) and emergency central venous decompression ( n = 1). Technical success was achieved in all cases, with restoration of patency of both brachiocephalic veins and the superior vena cava. Mean fluoroscopy time was 30.6 min. No immediate complications occurred. Primary stent patency was maintained during available follow-up (29–301 days; median 149 days). Discussion CERAC enables confluence-preserving bilateral reconstruction while minimizing stent overlap and maintaining favourable luminal geometry. Inspired by the Covered Endovascular Reconstruction of the Aortic Bifurcation, CERAC represents, to our knowledge, the first description of a fully covered, confluence-preserving reconstruction in this anatomical setting. Conclusion CERAC is a feasible endovascular option for selected SVCS cases involving the brachiocephalic confluence. Further studies are needed to evaluate long-term outcomes and to better define appropriate indications. Level of evidence Level V.

CVIR EndovascularVol. 9(1)
Policlinico San Matteo Fondazione (IT)
Openalex Percentile: Top 7%
Central Venous Catheters and Hemodialysis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.