Enhancing bioaccessibility of camellia seed oil through whey protein isolate–quercetin complex stabilized emulsions

Camellia seed oil (CSO) exhibits poor dispersibility and low bioaccessibility during digestion. In this study, a whey protein isolate–quercetin (WPI–Que) complex was developed to fabricate CSO-in-water emulsions. The optimal complex (10 mg Que. was dissolved in 100 mL WPI solution) showed favorable physicochemical and emulsifying properties, and the formation of the complex originated from quercetin-induced conformational changes of WPI structure. Furthermore, the emulsion consisting of 5 g CSO and 10 mL emulsifier solution exhibited a uniform droplet distribution and an absolute zeta potential above 30 mV. More importantly, the emulsion exhibited higher bioaccessibility compared to bulk oil, with the maximum FFA release of 69.33 ± 0.99% and lipolysis rate of 0.0531 min −1 . These findings suggest that the WPI–Que complex can be used as emulsifier for constructing CSO delivery in functional food systems.

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Publication Details

Journal
Food Chemistry X
Published
2026-09-16
DOI
https://doi.org/10.1016/j.fochx.2026.104480
Primary Topic
Proteins in Food Systems
Type
article
Field-Weighted Citation Impact
0.00

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article

Enhancing bioaccessibility of camellia seed oil through whey protein isolate–quercetin complex stabilized emulsions

Yong Zhu, Likang Qin, Wenxin Zha, Haiyan Zhong et al.
Food Chemistry X
Proteins in Food Systems
article

Enhancing bioaccessibility of camellia seed oil through whey protein isolate–quercetin complex stabilized emulsions

Yong Zhu, Likang Qin, Wenxin Zha, Haiyan Zhong, Yu Yuan, Qingqing Li
article en

Abstract

Camellia seed oil (CSO) exhibits poor dispersibility and low bioaccessibility during digestion. In this study, a whey protein isolate–quercetin (WPI–Que) complex was developed to fabricate CSO-in-water emulsions. The optimal complex (10 mg Que. was dissolved in 100 mL WPI solution) showed favorable physicochemical and emulsifying properties, and the formation of the complex originated from quercetin-induced conformational changes of WPI structure. Furthermore, the emulsion consisting of 5 g CSO and 10 mL emulsifier solution exhibited a uniform droplet distribution and an absolute zeta potential above 30 mV. More importantly, the emulsion exhibited higher bioaccessibility compared to bulk oil, with the maximum FFA release of 69.33 ± 0.99% and lipolysis rate of 0.0531 min −1 . These findings suggest that the WPI–Que complex can be used as emulsifier for constructing CSO delivery in functional food systems.

Food Chemistry XVol. 39
Central South University of Forestry and Technology (CN), Central South University (CN), Guizhou University (CN), Zunyi Medical University (CN), Guizhou Academy of Agricultural Sciences (CN)
National Natural Science Foundation of China
Zero hunger
Openalex Percentile: Top 14%
Proteins in Food Systems
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Enhancing bioaccessibility of camellia seed oil through whey protein isolate–quercetin complex stabilized emulsions — Yong Zhu, Likang Qin, et al. · Food Chemistry X (2026) | TGRS Research Map | TGRS