A rare case report: Malignant transformation of lichen planus
Lichen planus is a chronic inflammatory disease that mainly affects the skin and mucous membranes. Malignant transformation is uncommon and is most frequently reported in oral or genital lesions. We report a rare case of cutaneous lichen planus on the left lower leg that transformed into squamous cell carcinoma with left inguinal lymph node metastasis. 18F-FDG PET/CT demonstrated increased uptake in the primary skin lesion and metastatic lymph nodes, providing important information for staging and treatment planning. This case highlights the potential malignant transformation of long-standing cutaneous lichen planus and the value of PET/CT in evaluating disease extent
Authors
- Xunrui Zhao
- Yongzhu Pu
- 谢燃
- Long Chen (ORCID: https://orcid.org/0000-0002-2979-5033)
- Chengtao Feng (ORCID: https://orcid.org/0000-0001-5539-9221)
- HaiCheng He
- Yujie Du
Institutions
- Kunming Medical University (CN)
- People's Hospital of Bishan District (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Radiology Case Reports
- Published
- 2026-09-15
- DOI
- https://doi.org/10.1016/j.radcr.2026.08.045
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00