The Collective Action of Firms on Regulatory Science: Mechanistic Toxicology as a Market‐Making Epistemic Strategy in the R&D Agrochemical Industry

ABSTRACT The influence of agrochemical firms on testing and risk assessment standards constitutes a central yet understudied dimension of the political economy of agrochemicals and the formation of a corporate‐dominated global pesticide regime. How leading R&D firms—formally positioned as competitors—have converged in the production and dissemination of specific forms of knowledge, and how this convergence shapes the epistemic foundations of agrochemical regulation, remains insufficiently explored. This paper examines how, from the 1990s onward, major agrochemical firms collectively invested in mechanistic toxicology as a means of de‐risking their innovation pipelines and facilitating the regulatory approval of active substances. It argues that mechanistic toxicology, and particularly the qualification of toxicological modes of action of pesticides, became the cornerstone of a shared epistemic strategy that aligned regulatory standards with the industrial and financial imperatives of R&D‐intensive firms. By demonstrating how knowledge production operates as a strategic instrument in structuring the conditions of pesticide commercialisation, the article contributes to political economy and science and technology studies scholarship on the co‐production of markets, regulation and scientific knowledge.

Authors

Institutions

Publication Details

Journal
Journal of Agrarian Change
Published
2026-09-16
DOI
https://doi.org/10.1111/joac.70117
Primary Topic
Genetically Modified Organisms Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

The Collective Action of Firms on Regulatory Science: Mechanistic Toxicology as a Market‐Making Epistemic Strategy in the R&D Agrochemical Industry

David Demortain
Journal of Agrarian Change
Genetically Modified Organisms Research
article

The Collective Action of Firms on Regulatory Science: Mechanistic Toxicology as a Market‐Making Epistemic Strategy in the R&D Agrochemical Industry

David Demortain
article en

Abstract

ABSTRACT The influence of agrochemical firms on testing and risk assessment standards constitutes a central yet understudied dimension of the political economy of agrochemicals and the formation of a corporate‐dominated global pesticide regime. How leading R&D firms—formally positioned as competitors—have converged in the production and dissemination of specific forms of knowledge, and how this convergence shapes the epistemic foundations of agrochemical regulation, remains insufficiently explored. This paper examines how, from the 1990s onward, major agrochemical firms collectively invested in mechanistic toxicology as a means of de‐risking their innovation pipelines and facilitating the regulatory approval of active substances. It argues that mechanistic toxicology, and particularly the qualification of toxicological modes of action of pesticides, became the cornerstone of a shared epistemic strategy that aligned regulatory standards with the industrial and financial imperatives of R&D‐intensive firms. By demonstrating how knowledge production operates as a strategic instrument in structuring the conditions of pesticide commercialisation, the article contributes to political economy and science and technology studies scholarship on the co‐production of markets, regulation and scientific knowledge.

Journal of Agrarian Change
Centre National de la Recherche Scientifique (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Laboratoire Interdisciplinaire Solidarités Sociétés Territoires (FR), Laboratoire Interdisciplinaire Sciences, Innovations, Sociétés (FR)
Industry, innovation and infrastructure
Openalex Percentile: Top 13%
Genetically Modified Organisms Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

The Collective Action of Firms on Regulatory Science: Mechanistic Toxicology as a Market‐Making Epistemic Strategy in the R&D Agrochemical Industry — David Demortain · Journal of Agrarian Change (2026) | TGRS Research Map | TGRS