Beyond Pigment Loss: Three Therapeutic Objectives in Vitiligo

Vitiligo entails three therapeutic objectives: control of autoimmune activity, restoration of melanocyte function, and interruption of disease memory. Distinguishing these goals can refine clinical management, trial endpoints, and therapeutic development in vitiligo and other immune-mediated skin diseases.

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Publication Details

Journal
International Journal of Dermatology
Published
2026-09-15
DOI
https://doi.org/10.1111/ijd.70686
Primary Topic
melanin and skin pigmentation
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond Pigment Loss: Three Therapeutic Objectives in Vitiligo

Davinder Parsad, Julia Sigova, Torello Lotti, Yan Valle
International Journal of Dermatology
melanin and skin pigmentation
article

Beyond Pigment Loss: Three Therapeutic Objectives in Vitiligo

Davinder Parsad, Julia Sigova, Torello Lotti, Yan Valle
article en

Abstract

Vitiligo entails three therapeutic objectives: control of autoimmune activity, restoration of melanocyte function, and interruption of disease memory. Distinguishing these goals can refine clinical management, trial endpoints, and therapeutic development in vitiligo and other immune-mediated skin diseases.

International Journal of Dermatology
ZHAW Zurich University of Applied Sciences (CH), Istituto Superiore di Sanità (IT), Marconi University (IT), Pirogov Russian National Research Medical University (RU), Vitiligo and Pigmentation Institute of Southern California (US), Post Graduate Institute of Medical Education and Research (IN)
Good health and well-being, Zero hunger
Openalex Percentile: Top 14%
melanin and skin pigmentation
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Beyond Pigment Loss: Three Therapeutic Objectives in Vitiligo — Davinder Parsad, Julia Sigova, et al. · International Journal of Dermatology (2026) | TGRS Research Map | TGRS