Acute coronary syndrome secondary to aortic valve papillary fibroelastoma: a case report

Fibroelastoma is a rare and benign heart tumor. However, it can have serious complications. The originality of this case lies in its clinical presentation which was unusual. We, herein, report the case of a 61-year-old North African female patient, with a history of diabetes, hypertension, sleep apnea syndrome, and non explored ischemic stroke. The patient was admitted for acute coronary syndrome without ST-segment elevation at very high risk. Diagnosis of papillary fibroelastoma on the aortic valve was made based on the etiological assessment, particularly on cardiac imaging. The patient underwent surgical excision and this diagnosis was confirmed by the histopathological examination of the surgical specimen. The atypical presentation of acute coronary syndrome (ACS) was related to a complete and transient obstruction of the left main coronary artery ostium by the aortic papillary fibroelastoma. Multimodality cardiac imaging played a crucial role in the etiological diagnosis of the ACS.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-09-16
DOI
https://doi.org/10.1186/s13256-026-06470-5
Primary Topic
Cardiac tumors and thrombi
Type
article
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article

Acute coronary syndrome secondary to aortic valve papillary fibroelastoma: a case report

Mehdi Slim, Sameh Ben Farhat, Khouloud Ben Lazreg, R. Gribaa et al.
Journal of Medical Case Reports
Cardiac tumors and thrombi
article

Acute coronary syndrome secondary to aortic valve papillary fibroelastoma: a case report

Mehdi Slim, Sameh Ben Farhat, Khouloud Ben Lazreg, R. Gribaa, Elyes Neffati, M. Kacem, Houssem Thabet, Imen Mgarrech, Oussama Belkacem, Nadia Mama, Sofien Jerbi
article en

Abstract

Fibroelastoma is a rare and benign heart tumor. However, it can have serious complications. The originality of this case lies in its clinical presentation which was unusual. We, herein, report the case of a 61-year-old North African female patient, with a history of diabetes, hypertension, sleep apnea syndrome, and non explored ischemic stroke. The patient was admitted for acute coronary syndrome without ST-segment elevation at very high risk. Diagnosis of papillary fibroelastoma on the aortic valve was made based on the etiological assessment, particularly on cardiac imaging. The patient underwent surgical excision and this diagnosis was confirmed by the histopathological examination of the surgical specimen. The atypical presentation of acute coronary syndrome (ACS) was related to a complete and transient obstruction of the left main coronary artery ostium by the aortic papillary fibroelastoma. Multimodality cardiac imaging played a crucial role in the etiological diagnosis of the ACS.

Journal of Medical Case Reports
Hôpital Sahloul (TN)
Good health and well-being
Openalex Percentile: Top 11%
Cardiac tumors and thrombi
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Acute coronary syndrome secondary to aortic valve papillary fibroelastoma: a case report — Mehdi Slim, Sameh Ben Farhat, et al. · Journal of Medical Case Reports (2026) | TGRS Research Map | TGRS