The association of clinical empathy with health-related quality-of-life outcomes in patients with fibromyalgia: a retrospective cohort study

PURPOSE: To measure the association of clinical empathy with health-related quality-of-life (HRQOL) outcomes in patients with fibromyalgia. MATERIALS AND METHODS: A retrospective cohort study was conducted within the Pain Registry for Epidemiological, Clinical, and Interventional Studies and Innovation. The Consultation and Relational Empathy (CARE) measure was completed by 226 patients with fibromyalgia to assemble cohorts exposed to low, moderate, or high levels of clinical empathy. Patients were followed at quarterly intervals over 12 months to measure T-scores for anxiety, depression, fatigue, and sleep disturbance using the Patient-Reported Outcomes Measurement Information System. RESULTS: The mean (SD) age of patients was 52.8 (12.1) years and 204 (90.3%) were female. The median (IQR) CARE measure score was 40 (28-50). After adjusting for potential confounders, the high clinical empathy group reported lesser HRQOL deficits than the low clinical empathy group on all measures. The mean difference (95% CI) for depression was -4.7 (-7.3 to -2.1), which surpassed the threshold for a medium effect size. Other differences represented small effects. CONCLUSIONS: High levels of clinical empathy were associated with better HRQOL outcomes over 12 months in patients with fibromyalgia. Cultivating greater clinical empathy in clinicians who treat patients with fibromyalgia may improve outcomes.

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Journal
Disability and Rehabilitation
Published
2026-09-15
DOI
https://doi.org/10.1080/09638288.2026.2729411
Primary Topic
Empathy and Medical Education
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article
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article

The association of clinical empathy with health-related quality-of-life outcomes in patients with fibromyalgia: a retrospective cohort study

John C. Licciardone, Subhash Aryal, Anish Reddy, Ruth A. Zachariah et al.
Disability and Rehabilitation
Empathy and Medical Education
article

The association of clinical empathy with health-related quality-of-life outcomes in patients with fibromyalgia: a retrospective cohort study

John C. Licciardone, Subhash Aryal, Anish Reddy, Ruth A. Zachariah, Myah Bowen, Matthew Medved, Madelyn A. Jones
article en

Abstract

PURPOSE: To measure the association of clinical empathy with health-related quality-of-life (HRQOL) outcomes in patients with fibromyalgia. MATERIALS AND METHODS: A retrospective cohort study was conducted within the Pain Registry for Epidemiological, Clinical, and Interventional Studies and Innovation. The Consultation and Relational Empathy (CARE) measure was completed by 226 patients with fibromyalgia to assemble cohorts exposed to low, moderate, or high levels of clinical empathy. Patients were followed at quarterly intervals over 12 months to measure T-scores for anxiety, depression, fatigue, and sleep disturbance using the Patient-Reported Outcomes Measurement Information System. RESULTS: The mean (SD) age of patients was 52.8 (12.1) years and 204 (90.3%) were female. The median (IQR) CARE measure score was 40 (28-50). After adjusting for potential confounders, the high clinical empathy group reported lesser HRQOL deficits than the low clinical empathy group on all measures. The mean difference (95% CI) for depression was -4.7 (-7.3 to -2.1), which surpassed the threshold for a medium effect size. Other differences represented small effects. CONCLUSIONS: High levels of clinical empathy were associated with better HRQOL outcomes over 12 months in patients with fibromyalgia. Cultivating greater clinical empathy in clinicians who treat patients with fibromyalgia may improve outcomes.

Disability and Rehabilitation
University of North Texas (US), Johns Hopkins University (US), University of North Texas Health Science Center (US)
Industry, innovation and infrastructure
Openalex Percentile: Top 10%
Empathy and Medical Education
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The association of clinical empathy with health-related quality-of-life outcomes in patients with fibromyalgia: a retrospective cohort study — John C. Licciardone, Subhash Aryal, et al. · Disability and Rehabilitation (2026) | TGRS Research Map | TGRS