MALT lymphoma mimicking IgG4-related disease

A 75-year-old man presented with left eye fullness, proptosis, and bilateral lacrimal gland enlargement with elevated serum IgG4 levels, initially suggesting IgG4-related disease. However, lacrimal gland biopsy revealed MALT lymphoma. This case highlights the overlapping clinical features of IgG4-related disease and lymphoma and emphasizes the importance of histopathological confirmation before initiating treatment.

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Publication Details

Journal
European Journal of Ophthalmology
Published
2026-09-16
DOI
https://doi.org/10.1177/11206721261489031
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

MALT lymphoma mimicking IgG4-related disease

Chun‐Chieh Lai, Chun-Hsiang Chang
European Journal of Ophthalmology
IgG4-Related and Inflammatory Diseases
article

MALT lymphoma mimicking IgG4-related disease

Chun‐Chieh Lai, Chun-Hsiang Chang
article en

Abstract

A 75-year-old man presented with left eye fullness, proptosis, and bilateral lacrimal gland enlargement with elevated serum IgG4 levels, initially suggesting IgG4-related disease. However, lacrimal gland biopsy revealed MALT lymphoma. This case highlights the overlapping clinical features of IgG4-related disease and lymphoma and emphasizes the importance of histopathological confirmation before initiating treatment.

European Journal of Ophthalmology
National Cheng Kung University Hospital (TW), National Cheng Kung University (TW)
Good health and well-being
Openalex Percentile: Top 10%
IgG4-Related and Inflammatory Diseases
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