Undifferentiated Pleomorphic Sarcoma with a Likely Nonfunctional EWSR1::NF2 Fusion and Complex Genomic Background: A Case Report

EWSR1 fusions are recurrent genetic alterations in a wide spectrum of mesenchymal tumors and are often associated with specific clinicopathologic entities. However, the presence of an EWSR1 rearrangement does not always indicate a functional or disease-defining fusion.