Clinical profile and outcomes of central retinal vein occlusion in a Hispanic-Mexican population: a real-world study

Background: Central retinal vein occlusion (RVO) is a relevant and frequent retinal vascular disease with considerable visual morbidity.Few reports have characterized the clinical profile and outcomes of the aforementioned disorder in Hispanic-Mexican populations.Materials and methods: The present study has a retrospective, observational, and analytical design.Patients of either gender or any age with central RVO in an ophthalmological academic center were included in the study.Sociodemographic, clinical, and outcomes data were recorded and analyzed.Only patients who were treatment naïve when arriving at the study's center were included for the clinical and outcomes part of the analysis.Results: One hundred and fifty-four eyes of 150 patients were included in the present study.Female-to-male ratio was 1.23:1, while the mean age was 65.20 years (standard deviation 14.5).Hypertension, diabetes mellitus, and any type of glaucoma were present in 42.7%, 27.3%, and 26.0% of patients, respectively.Sixty patients (44.4%) were classified as an ischemic occlusion, and 75 (55.6%)as a non-ischemic.Initial and final visual acuities were better for non-ischemic occlusions.Most patients improved their visual acuity after treatment with intravitreal anti-vascular endothelial growth factor, but the non-ischemic occlusions improved more lines than the ischemic ones.Neovascularization of the disc, hemovitreous, and neovascular glaucoma were more common on the ischemic occlusions, while macular edema and neovascularization elsewhere had no statistically significant difference between both groups.Conclusion: The clinical profile and outcomes of the Hispanic-Mexican patient with central RVO are similar to other previously reported populations, with final visual acuity and complications rate heavily influenced by the ischemic status of the occlusion.