Preventing Surgical Site Infections: Ethical and Operational Imperatives for the Global Health Agenda

Background: Surgical site infections (SSIs) remain a major cause of morbidity, mortality, and inequity worldwide. Many SSIs are preventable and represent an important indicator of surgical quality and patient safety. Methods: Evidence and implementation experiences on SSI prevention were reviewed, focusing on infection prevention and control (IPC), antimicrobial stewardship (AMS), antimicrobial resistance (AMR), quality improvement, surveillance, safety culture, human factors, and emerging technologies. Results: Multimodal, context-adapted IPC interventions can substantially reduce SSI incidence without major capital investment. Persistent gaps in infrastructure, guideline implementation, surveillance, and environmental controls remain important challenges. AMR further emphasizes the need to integrate AMS into surgical safety frameworks. Artificial intelligence and objective diagnostic technologies may improve surveillance and early SSI detection. Summary: SSI prevention is both a clinical necessity and an ethical imperative. Global surgery strategies should integrate IPC, AMS, surveillance, safety culture, and innovative technologies to advance equity, quality, and safety in surgical care worldwide.

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Publication Details

Journal
Surgical Infections
Published
2026-09-14
DOI
https://doi.org/10.1177/10962964261488660
Primary Topic
Surgical site infection prevention
Type
article
Field-Weighted Citation Impact
0.00
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article

Preventing Surgical Site Infections: Ethical and Operational Imperatives for the Global Health Agenda

Francesco M. Labricciosa, Inés Rubio‐Pérez, Emmanuel A. Ameh, Keita Morikane et al.
Surgical Infections
Surgical site infection prevention
article

Preventing Surgical Site Infections: Ethical and Operational Imperatives for the Global Health Agenda

Francesco M. Labricciosa, Inés Rubio‐Pérez, Emmanuel A. Ameh, Keita Morikane, Philip S. Barie, Sanjay Marwah, Carlos Roberto Veiga Kiffer, Massimo Sartelli, Mayur Narayan, Robert G. Sawyer, Divya Kewalramani, Peter M. Nthumba, Kemal Rasa, Vihar Kotecha, Alberto R. Ferreres, Federico Coccolini, Fausto Catena, Claire Kilpatrick, Miguel A. Cainzos, Jeremiah Seni
article en

Abstract

Background: Surgical site infections (SSIs) remain a major cause of morbidity, mortality, and inequity worldwide. Many SSIs are preventable and represent an important indicator of surgical quality and patient safety. Methods: Evidence and implementation experiences on SSI prevention were reviewed, focusing on infection prevention and control (IPC), antimicrobial stewardship (AMS), antimicrobial resistance (AMR), quality improvement, surveillance, safety culture, human factors, and emerging technologies. Results: Multimodal, context-adapted IPC interventions can substantially reduce SSI incidence without major capital investment. Persistent gaps in infrastructure, guideline implementation, surveillance, and environmental controls remain important challenges. AMR further emphasizes the need to integrate AMS into surgical safety frameworks. Artificial intelligence and objective diagnostic technologies may improve surveillance and early SSI detection. Summary: SSI prevention is both a clinical necessity and an ethical imperative. Global surgery strategies should integrate IPC, AMS, surveillance, safety culture, and innovative technologies to advance equity, quality, and safety in surgical care worldwide.

Surgical Infections
Robert Wood Johnson University Hospital (US), Anadolu University (TR), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (IN), Western Michigan University (US), Glasgow Caledonian University (GB), Cornell University (US), Universidad de Buenos Aires (AR), Catholic University of Health and Allied Sciences (TZ), Hospital Universitario La Paz (ES), Johnson University (US), National Hospital Abuja (NG), Kijabe Hospital (KE), Instituto de Investigación Sanitaria de Santiago (ES), Associação Paulista de Medicina (BR), Nile University of Nigeria (NG), Azienda Ospedaliera Universitaria Pisana (IT), Yamagata University Hospital (JP), Ospedale di Macerata, Vanderbilt University Medical Center (US), University of Bologna (IT)
Industry, innovation and infrastructure
Openalex Percentile: Top 9%
Surgical site infection prevention
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