Association Between High-Density Lipoprotein Cholesterol Efflux Capacity and Renal Function in Patients With Type 2 Diabetes
Background: The cholesterol efflux capacity (CEC) of high-density lipoprotein (HDL) (HDL-CEC) is inversely associated with atherosclerotic cardiovascular disease. Type 2 diabetes mellitus (T2DM) is frequently complicated by chronic kidney disease (CKD), usually associated with increased homocysteine (Hcy), and these conditions are likely to be involved in HDL dysfunction. However, the relationship between HDL-CEC and CKD, as well as Hcy levels in patients with T2DM remains unclear.
Authors
- Takahiro Hadano
- Keiichiro Matoba (ORCID: https://orcid.org/0000-0003-0041-0483)
- Sadako Matsui (ORCID: https://orcid.org/0000-0002-0117-266X)
- Kei Fujimoto (ORCID: https://orcid.org/0000-0002-8813-9263)
- Chika Hiraishi
- Hiroshi Yoshida
Institutions
- Jikei University School of Medicine (JP)
- University of Tsukuba (JP)
- Japan Women's University (JP)
- Clinical Hospital No. 8 (RU)
- Jikei University Kashiwa hospital (JP)
Publication Details
- Journal
- Circulation Reports
- Published
- 2026-09-14
- DOI
- https://doi.org/10.1253/circrep.cr-26-0219
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jikei University School of Medicine
- Japan Society for the Promotion of Science