Invitro Study of the Antioxidant and Anti-Inflammatory Potential of Rauvolfia Vomitoria Afzel Leaf Crude Extract
Oxidative stress is a physiological term that describes an imbalance between reactive oxygen species (ROS) generation and the body’s ability to detoxify them or repair the resulting damage. Scientific validation of traditional medicinal plants is essential for their integration into modern healthcare systems and pharmaceutical developments. This study aimed to fill the existing knowledge gap by examining the antioxidant potential of R. vomitoria crude ex3tract using multiple assay methods and comparing the results with standard ascorbic acid. Rauvofia vomitoria leaves were powdered and soaked in 100% methanol for 48 hours at room temperature with occasional agitations.. The extract demonstrated notable inhibitions of protein denaturation, trypsin activity, and DNA oxidation to fight inflammation. The study provided compelling evidence of anti-inflammatory potential of Rauvolfia vomitoria.
Authors
- A. S. Arowolo
- A. O. Akinyemi
- Bamigboye Adeola
Institutions
- Ladoke Akintola University of Technology (NG)
Publication Details
- Journal
- Iconic Research and Engineering Journals
- Published
- 2026-09-14
- DOI
- https://doi.org/10.64388/irev10i3-1722821
- Primary Topic
- Morinda citrifolia extract uses
- Type
- article
- Field-Weighted Citation Impact
- 0.00