Invitro Study of the Antioxidant and Anti-Inflammatory Potential of Rauvolfia Vomitoria Afzel Leaf Crude Extract

Oxidative stress is a physiological term that describes an imbalance between reactive oxygen species (ROS) generation and the body’s ability to detoxify them or repair the resulting damage. Scientific validation of traditional medicinal plants is essential for their integration into modern healthcare systems and pharmaceutical developments. This study aimed to fill the existing knowledge gap by examining the antioxidant potential of R. vomitoria crude ex3tract using multiple assay methods and comparing the results with standard ascorbic acid. Rauvofia vomitoria leaves were powdered and soaked in 100% methanol for 48 hours at room temperature with occasional agitations.. The extract demonstrated notable inhibitions of protein denaturation, trypsin activity, and DNA oxidation to fight inflammation. The study provided compelling evidence of anti-inflammatory potential of Rauvolfia vomitoria.

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Journal
Iconic Research and Engineering Journals
Published
2026-09-14
DOI
https://doi.org/10.64388/irev10i3-1722821
Primary Topic
Morinda citrifolia extract uses
Type
article
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article

Invitro Study of the Antioxidant and Anti-Inflammatory Potential of Rauvolfia Vomitoria Afzel Leaf Crude Extract

A. S. Arowolo, A. O. Akinyemi, Bamigboye Adeola
Iconic Research and Engineering Journals
Morinda citrifolia extract uses
article

Invitro Study of the Antioxidant and Anti-Inflammatory Potential of Rauvolfia Vomitoria Afzel Leaf Crude Extract

A. S. Arowolo, A. O. Akinyemi, Bamigboye Adeola
article en

Abstract

Oxidative stress is a physiological term that describes an imbalance between reactive oxygen species (ROS) generation and the body’s ability to detoxify them or repair the resulting damage. Scientific validation of traditional medicinal plants is essential for their integration into modern healthcare systems and pharmaceutical developments. This study aimed to fill the existing knowledge gap by examining the antioxidant potential of R. vomitoria crude ex3tract using multiple assay methods and comparing the results with standard ascorbic acid. Rauvofia vomitoria leaves were powdered and soaked in 100% methanol for 48 hours at room temperature with occasional agitations.. The extract demonstrated notable inhibitions of protein denaturation, trypsin activity, and DNA oxidation to fight inflammation. The study provided compelling evidence of anti-inflammatory potential of Rauvolfia vomitoria.

Iconic Research and Engineering JournalsVol. 10(3)
Ladoke Akintola University of Technology (NG)
Openalex Percentile: Top 6%
Morinda citrifolia extract uses
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Invitro Study of the Antioxidant and Anti-Inflammatory Potential of Rauvolfia Vomitoria Afzel Leaf Crude Extract — A. S. Arowolo, A. O. Akinyemi, et al. · Iconic Research and Engineering Journals (2026) | TGRS Research Map | TGRS