A Constraint‐Based Analytical Framework for Design‐Space Analysis and Material Screening of Tubular Multilayer Dielectric Elastomer Pumps for Extracorporeal Circulatory Applications

ABSTRACT Dielectric elastomer actuator (DEA) pumps generate fluid displacement through smooth, distributed deformation of compliant polymer membranes and are promising soft pumping modules for controlled extracorporeal circulatory platforms, such as mock circulatory loops and ex vivo organ‐perfusion systems. However, their hydraulic performance and electromechanically feasible operating space depend on strongly coupled material properties, structural parameters, loading conditions, and driving voltage. Here, we present a constraint‐based analytical framework for design‐space analysis and material screening of tubular multilayer DEA pumps under combined internal bias pressure and applied voltage. The framework enforces minimum elastic strain energy (for pressure head), minimum stroke volume (for flow rate), electromechanical coupling, maximum strain, and dielectric breakdown limits. It is benchmarked against quasi‐static finite‐element simulations, with a mean deviation below 0.05. With device‐specific empirical corrections, it also captures the observed resonance and the flow‐rate and pressure‐head trends in experiments. For a specified pump geometry and performance targets, the framework quickly narrows the design‐space and screens candidate DEs with feasible solutions. This framework as a specific example exhibits a practical design methodology by using a simplified analytical approach to narrow down the design‐space and the material‐selection space in tubular DEA pumps for extracorporeal circulatory applications.