Community-Acquired Klebsiella pneumoniae Meningitis With Liver Abscess and Neurological Sequelae in an Immunocompetent Adult: A Case Report

Klebsiella pneumoniae meningitis (KPM) is a rare but severe form of community-acquired bacterial meningitis that is often associated with high mortality and neurological sequelae.We report a 46-year-old previously healthy male who presented with acute altered mental status and high-grade fever.Cerebrospinal fluid analysis was consistent with bacterial meningitis, and cultures from the cerebrospinal fluid and blood showed Klebsiella pneumoniae (K.pneumoniae) growth.The clinical course of the patient was complicated with seizures and acute right-sided hemiplegia.Persistent fever (despite appropriate antimicrobial therapy) prompted further evaluation, which revealed a hepatic abscess.Percutaneous abscess drainage resulted in rapid clinical improvement and notable neurological recovery.This case highlights the importance of early recognition of K. pneumoniae as a potential cause of community-acquired meningitis and the need to actively search for an underlying primary source, particularly a liver abscess, when the clinical response to antibiotics is suboptimal.

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Journal
Cureus
Published
2026-09-14
DOI
https://doi.org/10.7759/cureus.116236
Primary Topic
Bacterial Infections and Vaccines
Type
article
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0.00
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article

Community-Acquired Klebsiella pneumoniae Meningitis With Liver Abscess and Neurological Sequelae in an Immunocompetent Adult: A Case Report

Leyla Kedir Bereka, Sheema Thomas Parakkal, Ghamdan Alsadeh, Ahmed S Rahal
Cureus
Bacterial Infections and Vaccines
article

Community-Acquired Klebsiella pneumoniae Meningitis With Liver Abscess and Neurological Sequelae in an Immunocompetent Adult: A Case Report

Leyla Kedir Bereka, Sheema Thomas Parakkal, Ghamdan Alsadeh, Ahmed S Rahal
article en

Abstract

Klebsiella pneumoniae meningitis (KPM) is a rare but severe form of community-acquired bacterial meningitis that is often associated with high mortality and neurological sequelae.We report a 46-year-old previously healthy male who presented with acute altered mental status and high-grade fever.Cerebrospinal fluid analysis was consistent with bacterial meningitis, and cultures from the cerebrospinal fluid and blood showed Klebsiella pneumoniae (K.pneumoniae) growth.The clinical course of the patient was complicated with seizures and acute right-sided hemiplegia.Persistent fever (despite appropriate antimicrobial therapy) prompted further evaluation, which revealed a hepatic abscess.Percutaneous abscess drainage resulted in rapid clinical improvement and notable neurological recovery.This case highlights the importance of early recognition of K. pneumoniae as a potential cause of community-acquired meningitis and the need to actively search for an underlying primary source, particularly a liver abscess, when the clinical response to antibiotics is suboptimal.

Cureus
Ras al-Khaimah Medical and Health Sciences University (AE)
Good health and well-being
Openalex Percentile: Top 14%
Bacterial Infections and Vaccines
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Community-Acquired Klebsiella pneumoniae Meningitis With Liver Abscess and Neurological Sequelae in an Immunocompetent Adult: A Case Report — Leyla Kedir Bereka, Sheema Thomas Parakkal, et al. · Cureus (2026) | TGRS Research Map | TGRS