The Effects of Robot-Assisted Physiotherapy on Motor and Cognitive Recovery in Individuals with Hemiparetic Stroke: A Pilot Randomized Controlled Trial

AimStroke often leads to persistent motor and cognitive impairments, which can significantly limit functional independence. This study aimed to investigate the effects of a robot-assisted physiotherapy program on motor and cognitive outcomes in individuals with hemiparetic stroke.MethodsTwenty individuals with hemiparetic stroke were randomly assigned to an experimental group (EG, n = 10), receiving robot-assisted physiotherapy (THERA-Trainer-based training) combined with Bobath exercises, or a control group (CG, n = 10), receiving patient-specific Bobath exercises alone. The Mini-Mental State Examination (MMSE) was administered at baseline to assess cognitive status. Outcome measures included the Digit Span Forward (DSF), Digit Span Backward (DSB), Frenchay Arm Test, Fugl-Meyer Assessment–Upper Extremity (FMA-UE), Fugl-Meyer Assessment–Lower Extremity (FMA-LE), Mini-Balance Evaluation Systems Test (Mini-BESTest), Timed Up and Go (TUG), Timed Up and Go Cognitive (TUG-C), and Five Times Sit-to-Stand (5STS). Oxygen saturation (SpO2) and heart rate (HR) were monitored at baseline, at the end of the 5STS, and 1 min after the test.ResultsThe EG demonstrated significantly greater improvements in both cognitive performance and upper and lower limb motor function compared to the CG (p < 0.05). In addition, the EG showed superior improvements in TUG (p = 0.001) and TUG-C (p < 0.001), enhanced post-test SpO2 recovery (p = 0.011), and reduced baseline HR (p = 0.001).ConclusionThese findings suggest that integrating robot-assisted physiotherapy into standard rehabilitation may provide clinically meaningful benefits in individuals with subacute stroke. The combined approach appears to enhance both motor and cognitive recovery, supporting improved functional independence.

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Publication Details

Journal
International Journal of Neuroscience
Published
2026-09-12
DOI
https://doi.org/10.1080/00207454.2026.2733273
Primary Topic
Stroke Rehabilitation and Recovery
Type
article
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article

The Effects of Robot-Assisted Physiotherapy on Motor and Cognitive Recovery in Individuals with Hemiparetic Stroke: A Pilot Randomized Controlled Trial

Fatma Kübra Çekok, Nurel Ertürk, Ali Memis Mutlu, Ayşenur Gökşen
International Journal of Neuroscience
Stroke Rehabilitation and Recovery
article

The Effects of Robot-Assisted Physiotherapy on Motor and Cognitive Recovery in Individuals with Hemiparetic Stroke: A Pilot Randomized Controlled Trial

Fatma Kübra Çekok, Nurel Ertürk, Ali Memis Mutlu, Ayşenur Gökşen
article en

Abstract

AimStroke often leads to persistent motor and cognitive impairments, which can significantly limit functional independence. This study aimed to investigate the effects of a robot-assisted physiotherapy program on motor and cognitive outcomes in individuals with hemiparetic stroke.MethodsTwenty individuals with hemiparetic stroke were randomly assigned to an experimental group (EG, n = 10), receiving robot-assisted physiotherapy (THERA-Trainer-based training) combined with Bobath exercises, or a control group (CG, n = 10), receiving patient-specific Bobath exercises alone. The Mini-Mental State Examination (MMSE) was administered at baseline to assess cognitive status. Outcome measures included the Digit Span Forward (DSF), Digit Span Backward (DSB), Frenchay Arm Test, Fugl-Meyer Assessment–Upper Extremity (FMA-UE), Fugl-Meyer Assessment–Lower Extremity (FMA-LE), Mini-Balance Evaluation Systems Test (Mini-BESTest), Timed Up and Go (TUG), Timed Up and Go Cognitive (TUG-C), and Five Times Sit-to-Stand (5STS). Oxygen saturation (SpO2) and heart rate (HR) were monitored at baseline, at the end of the 5STS, and 1 min after the test.ResultsThe EG demonstrated significantly greater improvements in both cognitive performance and upper and lower limb motor function compared to the CG (p < 0.05). In addition, the EG showed superior improvements in TUG (p = 0.001) and TUG-C (p < 0.001), enhanced post-test SpO2 recovery (p = 0.011), and reduced baseline HR (p = 0.001).ConclusionThese findings suggest that integrating robot-assisted physiotherapy into standard rehabilitation may provide clinically meaningful benefits in individuals with subacute stroke. The combined approach appears to enhance both motor and cognitive recovery, supporting improved functional independence.

International Journal of Neuroscience
Tarsus University (TR)
Openalex Percentile: Top 14%
Stroke Rehabilitation and Recovery
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