Stochastic modeling for uncertainty quantification in COVID-19 dynamics using Euler Maruyama approximation

We propose a stochastic extension of a compartmental epidemiological model for COVID-19 to describe the transmission dynamics in Bogotá, Colombia. To account for intrinsic variability in infection, incubation, recovery, and vaccination processes, random perturbations are incorporated into key model parameters. The resulting system of stochastic differential equations is approximated using the Euler-Maruyama method, enabling likelihood-based parameter estimation. We derive an extended basic reproduction number, along with its associated uncertainty, providing a statistically grounded measure of epidemic potential under varying conditions. Simulation results demonstrate that the proposed framework successfully captures the variability observed in the epidemiological data and highlights the importance of accounting for parameter uncertainty in public health decision-making. The model is statistically tractable, computationally efficient, and adaptable to other infectious diseases and urban settings. Possible extensions include incorporating reinfection dynamics, integrating additional data sources, and using Bayesian inference to enhance uncertainty quantification.

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Publication Details

Journal
Scientific Reports
Published
2026-09-12
DOI
https://doi.org/10.1038/s41598-026-67117-5
Primary Topic
COVID-19 epidemiological studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Stochastic modeling for uncertainty quantification in COVID-19 dynamics using Euler Maruyama approximation

Andrés Ríos-Gutiérrez, Viswanathan Arunachalam, Soledad Torres
Scientific Reports
COVID-19 epidemiological studies
article

Stochastic modeling for uncertainty quantification in COVID-19 dynamics using Euler Maruyama approximation

Andrés Ríos-Gutiérrez, Viswanathan Arunachalam, Soledad Torres
article en

Abstract

We propose a stochastic extension of a compartmental epidemiological model for COVID-19 to describe the transmission dynamics in Bogotá, Colombia. To account for intrinsic variability in infection, incubation, recovery, and vaccination processes, random perturbations are incorporated into key model parameters. The resulting system of stochastic differential equations is approximated using the Euler-Maruyama method, enabling likelihood-based parameter estimation. We derive an extended basic reproduction number, along with its associated uncertainty, providing a statistically grounded measure of epidemic potential under varying conditions. Simulation results demonstrate that the proposed framework successfully captures the variability observed in the epidemiological data and highlights the importance of accounting for parameter uncertainty in public health decision-making. The model is statistically tractable, computationally efficient, and adaptable to other infectious diseases and urban settings. Possible extensions include incorporating reinfection dynamics, integrating additional data sources, and using Bayesian inference to enhance uncertainty quantification.

Scientific Reports
Universidad Industrial de Santander (CO), Universidad Nacional de Colombia (CO), University of Valparaíso (CL)
Universidad Nacional de Colombia, Agencia Nacional de Investigación y Desarrollo
Good health and well-being
Openalex Percentile: Top 12%
COVID-19 epidemiological studies
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