Loopcity: An R package for the detection of chromatin loop communities from Hi-C data

Abstract Summary Chromatin loops identified from Hi-C data are often analyzed individually, but recent studies suggest that they are often organized into highly interconnected multi-loop communities, the biological meaning of which is still not fully understood. Here we describe loopcity, an R package that identifies multi-loop communities from Hi-C data via the construction and clustering of weighted interaction networks. Availability and Implementation Available on GitHub at https://github.com/sarmapar/loopcity (currently submitting to Bioconductor) Supplementary information Supplementary data are available at Bioinformatics Advances online.