Combined dorsal and ventral rhizotomy in non‐ambulatory individuals with mixed spastic bilateral cerebral palsy: A prospective registry analysis

Aim To establish the efficacy of combined dorsal and ventral rhizotomy (CDVR) and associated quality of life (QoL) changes in individuals with cerebral palsy (CP). Method This was a prospective and consecutive recruitment of patients undergoing CDVR analyzed using retrospective cohort analysis. Spasticity and dystonia were measured using the modified Ashworth and Barry–Albright Dystonia Scales at 3 months and 12 months after surgery. QoL was measured using the Caregiver Priorities and Child Health Index of Life with Disabilities. Results Thirty‐three patients (21 males, 12 females) underwent CDVR between 2020 and 2025 at an average age of 14 years 6 months; 91% were classified in Gross Motor Function Classification System level V. CDVR had a low complication rate (one wound infection and no cerebrospinal fluid leaks). Spasticity was improved in all patients at 12 months by a median of 2 levels (preoperative: 3.0 [3.0–4.0] vs 1.0 [1.0–1.25] at 1 year, p < 0.001). Dystonia improved at 12 months (preoperative: 17.5 [10.0–21.25] vs 8.0 [3.25–10.5] at 12 months, p = 0.016). The Caregiver Priorities and Child Health Index of Life with Disabilities scores indicated improved QoL at 12 months (33.8 [5.3] vs 48.1 [4.7], p = 0.012). All patients returned to their stander or gait assistive devices by 1 year. Interpretation CDVR is safe and effective in non‐ambulatory individuals with bilateral, mixed spastic‐dyskinetic CP and improves QoL without decreasing preoperative function.

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Journal
Developmental Medicine & Child Neurology
Published
2026-09-11
DOI
https://doi.org/10.1111/dmcn.70456
Primary Topic
Cerebral Palsy and Movement Disorders
Type
article
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article

Combined dorsal and ventral rhizotomy in non‐ambulatory individuals with mixed spastic bilateral cerebral palsy: A prospective registry analysis

Benjamin J. Shore, Kristin Buxton, Adam C. Glaser, Weston T. Northam et al.
Developmental Medicine & Child Neurology
Cerebral Palsy and Movement Disorders
article

Combined dorsal and ventral rhizotomy in non‐ambulatory individuals with mixed spastic bilateral cerebral palsy: A prospective registry analysis

Benjamin J. Shore, Kristin Buxton, Adam C. Glaser, Weston T. Northam, Juliana Mariani, Joon Hyeok Choi, Nahyun Kim
article en

Abstract

Aim To establish the efficacy of combined dorsal and ventral rhizotomy (CDVR) and associated quality of life (QoL) changes in individuals with cerebral palsy (CP). Method This was a prospective and consecutive recruitment of patients undergoing CDVR analyzed using retrospective cohort analysis. Spasticity and dystonia were measured using the modified Ashworth and Barry–Albright Dystonia Scales at 3 months and 12 months after surgery. QoL was measured using the Caregiver Priorities and Child Health Index of Life with Disabilities. Results Thirty‐three patients (21 males, 12 females) underwent CDVR between 2020 and 2025 at an average age of 14 years 6 months; 91% were classified in Gross Motor Function Classification System level V. CDVR had a low complication rate (one wound infection and no cerebrospinal fluid leaks). Spasticity was improved in all patients at 12 months by a median of 2 levels (preoperative: 3.0 [3.0–4.0] vs 1.0 [1.0–1.25] at 1 year, p < 0.001). Dystonia improved at 12 months (preoperative: 17.5 [10.0–21.25] vs 8.0 [3.25–10.5] at 12 months, p = 0.016). The Caregiver Priorities and Child Health Index of Life with Disabilities scores indicated improved QoL at 12 months (33.8 [5.3] vs 48.1 [4.7], p = 0.012). All patients returned to their stander or gait assistive devices by 1 year. Interpretation CDVR is safe and effective in non‐ambulatory individuals with bilateral, mixed spastic‐dyskinetic CP and improves QoL without decreasing preoperative function.

Developmental Medicine & Child Neurology
Brigham and Women's Hospital (US), Boston Children's Hospital (US), United Cerebral Palsy (US), Spaulding Rehabilitation Hospital (US), Boston Children's Museum (US)
Openalex Percentile: Top 10%
Cerebral Palsy and Movement Disorders
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