Intermolecular Non-Covalent Interactions in the Crystal Packing of Spirobarbiturates: A Hirshfeld Surface Analysis

Abstract Three spirocyclic barbituric acid derivatives, previously synthesized via the 1,3-dipolar cycloaddition of an azomethine ylide with substituted cyclopropenes in our earlier work, were investigated using Hirshfeld surface analysis based on single-crystal X-ray diffraction data. The intermolecular interactions were characterized and quantified via fingerprint plots, global surface descriptors, and interaction energy decomposition.

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Journal
Russian Journal of General Chemistry
Published
2026-09-12
DOI
https://doi.org/10.1134/s1070363226602127
Primary Topic
Crystallography and molecular interactions
Type
article
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Intermolecular Non-Covalent Interactions in the Crystal Packing of Spirobarbiturates: A Hirshfeld Surface Analysis

Alexander V. Stepakov, Vitali M. Boitsov, Arthur A. Puzyrkov, Ekaterina V. Berezhnaya et al.
Russian Journal of General Chemistry
Crystallography and molecular interactions
article

Intermolecular Non-Covalent Interactions in the Crystal Packing of Spirobarbiturates: A Hirshfeld Surface Analysis

Alexander V. Stepakov, Vitali M. Boitsov, Arthur A. Puzyrkov, Ekaterina V. Berezhnaya, Kristina A. Kim, Daria A. Zykova
article en

Abstract

Abstract Three spirocyclic barbituric acid derivatives, previously synthesized via the 1,3-dipolar cycloaddition of an azomethine ylide with substituted cyclopropenes in our earlier work, were investigated using Hirshfeld surface analysis based on single-crystal X-ray diffraction data. The intermolecular interactions were characterized and quantified via fingerprint plots, global surface descriptors, and interaction energy decomposition.

Russian Journal of General ChemistryVol. 96(10)
Saint Petersburg Academic University (RU), St Petersburg University (RU), St. Petersburg State Technological Institute (RU)
Openalex Percentile: Top 12%
Crystallography and molecular interactions
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Intermolecular Non-Covalent Interactions in the Crystal Packing of Spirobarbiturates: A Hirshfeld Surface Analysis — Alexander V. Stepakov, Vitali M. Boitsov, et al. · Russian Journal of General Chemistry (2026) | TGRS Research Map | TGRS