A Multimodal AI Framework for Medical Education: Integrating Adaptive Image Retrieval, Fast Synthesis, and LLM-Based Clinical Auditing

Access to reliable medical images is essential for clinical training. To address this need, this paper presents an extended version of MIRAGE, a multimodal retrieval and generation system that utilizes a shared latent space to process medical queries by retrieving real images from the ROCO dataset, generating synthetic scans, and providing LLM-based clinical descriptions alongside dual-concept visual comparisons. To overcome previous computational limits and the lack of clinical validation, we introduce three core enhancements: first, an Auto-α module to dynamically weight visual and textual similarities; second, the integration of LCM-LoRA to accelerate synthetic image generation; and third, an automated clinical auditor based on Gemini 2.5 Flash. Experimental results demonstrate that Auto-α improves retrieval accuracy for heterogeneous queries, reaching 38.83% Top-1 Recall over a 65,419-image gallery and outperforming nine fusion baselines evaluated under a unified configuration, with a controlled ablation attributing most of this gain to learning the weight rather than merely making it query-adaptive, while the LCM-LoRA module reduces computational costs by a factor of 12.5× in CPU environments, with a blinded radiologist evaluation confirming only a small drop in clinical quality. Furthermore, the clinical auditor achieves a 0.805 Pearson correlation against an expert radiologist, effectively correcting the systematic overestimation of traditional CLIP scores. Finally, the optimized platform is publicly deployed on Hugging Face.

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Publication Details

Journal
Journal of Imaging
Published
2026-09-11
DOI
https://doi.org/10.3390/jimaging12090438
Primary Topic
Multimodal Machine Learning Applications
Type
article
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article

A Multimodal AI Framework for Medical Education: Integrating Adaptive Image Retrieval, Fast Synthesis, and LLM-Based Clinical Auditing

Álvaro García‐Martín, Jesús Bescós, Cecilia Diana-Albelda, Mario Rubén Paz Campos et al.
Journal of Imaging
Multimodal Machine Learning Applications
article

A Multimodal AI Framework for Medical Education: Integrating Adaptive Image Retrieval, Fast Synthesis, and LLM-Based Clinical Auditing

Álvaro García‐Martín, Jesús Bescós, Cecilia Diana-Albelda, Mario Rubén Paz Campos, Miguel Díaz-Benito
article en

Abstract

Access to reliable medical images is essential for clinical training. To address this need, this paper presents an extended version of MIRAGE, a multimodal retrieval and generation system that utilizes a shared latent space to process medical queries by retrieving real images from the ROCO dataset, generating synthetic scans, and providing LLM-based clinical descriptions alongside dual-concept visual comparisons. To overcome previous computational limits and the lack of clinical validation, we introduce three core enhancements: first, an Auto-α module to dynamically weight visual and textual similarities; second, the integration of LCM-LoRA to accelerate synthetic image generation; and third, an automated clinical auditor based on Gemini 2.5 Flash. Experimental results demonstrate that Auto-α improves retrieval accuracy for heterogeneous queries, reaching 38.83% Top-1 Recall over a 65,419-image gallery and outperforming nine fusion baselines evaluated under a unified configuration, with a controlled ablation attributing most of this gain to learning the weight rather than merely making it query-adaptive, while the LCM-LoRA module reduces computational costs by a factor of 12.5× in CPU environments, with a blinded radiologist evaluation confirming only a small drop in clinical quality. Furthermore, the clinical auditor achieves a 0.805 Pearson correlation against an expert radiologist, effectively correcting the systematic overestimation of traditional CLIP scores. Finally, the optimized platform is publicly deployed on Hugging Face.

Journal of ImagingVol. 12(9)
Hospital Universitario de La Princesa (ES), Universidad Carlos III de Madrid (ES), Universidad Autónoma de Madrid (ES)
Quality Education
Openalex Percentile: Top 13%
Multimodal Machine Learning Applications
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